Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre

<i>Background and Objectives:</i> Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Lavinia-Lucia Matei, Călin Siliște, Sebastian Stoica, Gabriel-Cristian Bejan, Liviu-Nicolae Ghilencea, Dragoș Vinereanu
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	atrial fibrillation ablation atrial fibrillation recurrence continuous ECG monitoring Medicine (General) R5-920
Acceso en línea:	https://doaj.org/article/f8c9a18ff1d2404d9cfb5fe7873d80d9
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f8c9a18ff1d2404d9cfb5fe7873d80d9
record_format	dspace
spelling	oai:doaj.org-article:f8c9a18ff1d2404d9cfb5fe7873d80d92021-11-25T18:17:57ZPredictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre10.3390/medicina571111391648-91441010-660Xhttps://doaj.org/article/f8c9a18ff1d2404d9cfb5fe7873d80d92021-10-01T00:00:00Zhttps://www.mdpi.com/1648-9144/57/11/1139https://doaj.org/toc/1010-660Xhttps://doaj.org/toc/1648-9144<i>Background and Objectives:</i> Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include technically inhomogeneous interventions, and populations with different types of AF. The aim of our study was to assess and stratify the risk at 6 and 12 months for AFR after a single RFCA, in patients with paroxysmal AF, in a centre with low volume activity. <i>Materials and Methods:</i> We enrolled 40 patients who underwent an initial RFCA, followed by continuous 48 h ECG monitoring at 1, 3, 6, and 12 months. Patients self-monitored their cardiac activity by random daily radial pulse palpation or in the presence of palpitations. <i>Results:</i> Ten independent predictors for late AFR were identified, and a 6-month risk score was computed using three of them: AFR duration in the first month, number of AFR between 1 and 3 months, and supraventricular ectopics per 24 h at 6 months. The score can explain 59% of the AFR (<i>p</i> = 0.001). A further 12-month assessment identified three independent predictors. The presence of AFR between 6–12 months is the most important of them (OR = 23.11, 95% CI = 3.87–137.83, <i>p</i> = 0.001), explaining 45% of AFR over 1 year. The risk scores at 6 and 12 months were internally validated. <i>Conclusions:</i> The 6-month score proved to be a useful tool in guiding further strategy for patients with a low risk, while a longer follow-up to 12 months may avoid unnecessary early reinterventions.Lavinia-Lucia MateiCălin SilișteSebastian StoicaGabriel-Cristian BejanLiviu-Nicolae GhilenceaDragoș VinereanuMDPI AGarticleatrial fibrillationablationatrial fibrillation recurrencecontinuous ECG monitoringMedicine (General)R5-920ENMedicina, Vol 57, Iss 1139, p 1139 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	atrial fibrillation ablation atrial fibrillation recurrence continuous ECG monitoring Medicine (General) R5-920
spellingShingle	atrial fibrillation ablation atrial fibrillation recurrence continuous ECG monitoring Medicine (General) R5-920 Lavinia-Lucia Matei Călin Siliște Sebastian Stoica Gabriel-Cristian Bejan Liviu-Nicolae Ghilencea Dragoș Vinereanu Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
description	<i>Background and Objectives:</i> Atrial fibrillation recurrences (AFR) after radiofrequency catheter ablation (RFCA) are not uncommon, up to 65% of patients having relapses in the first year. However, current data are based mainly on studies from centres with a large volume of ablations, as they include technically inhomogeneous interventions, and populations with different types of AF. The aim of our study was to assess and stratify the risk at 6 and 12 months for AFR after a single RFCA, in patients with paroxysmal AF, in a centre with low volume activity. <i>Materials and Methods:</i> We enrolled 40 patients who underwent an initial RFCA, followed by continuous 48 h ECG monitoring at 1, 3, 6, and 12 months. Patients self-monitored their cardiac activity by random daily radial pulse palpation or in the presence of palpitations. <i>Results:</i> Ten independent predictors for late AFR were identified, and a 6-month risk score was computed using three of them: AFR duration in the first month, number of AFR between 1 and 3 months, and supraventricular ectopics per 24 h at 6 months. The score can explain 59% of the AFR (<i>p</i> = 0.001). A further 12-month assessment identified three independent predictors. The presence of AFR between 6–12 months is the most important of them (OR = 23.11, 95% CI = 3.87–137.83, <i>p</i> = 0.001), explaining 45% of AFR over 1 year. The risk scores at 6 and 12 months were internally validated. <i>Conclusions:</i> The 6-month score proved to be a useful tool in guiding further strategy for patients with a low risk, while a longer follow-up to 12 months may avoid unnecessary early reinterventions.
format	article
author	Lavinia-Lucia Matei Călin Siliște Sebastian Stoica Gabriel-Cristian Bejan Liviu-Nicolae Ghilencea Dragoș Vinereanu
author_facet	Lavinia-Lucia Matei Călin Siliște Sebastian Stoica Gabriel-Cristian Bejan Liviu-Nicolae Ghilencea Dragoș Vinereanu
author_sort	Lavinia-Lucia Matei
title	Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_short	Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_full	Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_fullStr	Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_full_unstemmed	Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre
title_sort	predictors of atrial fibrillation recurrences after a first radiofrequency catheter ablation intervention for paroxysmal atrial fibrillation—experience of a low volume ablation centre
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/f8c9a18ff1d2404d9cfb5fe7873d80d9
work_keys_str_mv	AT lavinialuciamatei predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre AT calinsiliste predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre AT sebastianstoica predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre AT gabrielcristianbejan predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre AT liviunicolaeghilencea predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre AT dragosvinereanu predictorsofatrialfibrillationrecurrencesafterafirstradiofrequencycatheterablationinterventionforparoxysmalatrialfibrillationexperienceofalowvolumeablationcentre
_version_	1718411416749211648

Predictors of Atrial Fibrillation Recurrences after a First Radiofrequency Catheter Ablation Intervention for Paroxysmal Atrial Fibrillation—Experience of a Low Volume Ablation Centre

Ejemplares similares