A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis

There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we...

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Autores principales:	Nicolas Roydon Smoll, Arifuzzman Khan, Jacina Walker, Jamie McMahon, Michael Kirk, Gulam Khandaker
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f8ce4e93aae74e2a812c194080a6238f
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spelling	oai:doaj.org-article:f8ce4e93aae74e2a812c194080a6238f2021-11-11T06:44:19ZA norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis1932-6203https://doaj.org/article/f8ce4e93aae74e2a812c194080a6238f2021-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC8562815/?tool=EBIhttps://doaj.org/toc/1932-6203There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we performed an in-depth analysis of a gastroenteritis outbreak to examine the patterns of transmissions, household attack rates and the basic reproduction number (R0) for Norovirus in a child-care facility. We used data from parental interviews of suspected cases sent home with gastroenteritis at a child-care center between 24th of August and 18th of September 2020. A total of 52 persons in 19 household clusters were symptomatic in this outbreak investigation. Of all transmissions, 23 (46.9%) occurred in the child-care center, the rest occurring in households. We found a household attack rate of 36.5% (95% CI 27.3, 47.1%). Serial intervals were estimated as mean 2.5 ± SD1.45 days. The R0, using time-dependent methods during the growth phase of the outbreak (days 2 to 8) was 2.4 (95% CI 1.50, 3.50). The count of affected persons of a child-care center norovirus outbreak is approximately double the count of the total symptomatic staff and attending children. In the study setting, each symptomatic child-care attendee likely infected one other child-care attendee or staff and just over one household contact on average.Nicolas Roydon SmollArifuzzman KhanJacina WalkerJamie McMahonMichael KirkGulam KhandakerPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 16, Iss 11 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
description	There is a large burden of norovirus disease in child-care centers in Australia and around the world. Despite the ubiquity of norovirus outbreaks in child-care centers, little is known about the extent of this burden within the child-care center and the surrounding household clusters. Therefore, we performed an in-depth analysis of a gastroenteritis outbreak to examine the patterns of transmissions, household attack rates and the basic reproduction number (R0) for Norovirus in a child-care facility. We used data from parental interviews of suspected cases sent home with gastroenteritis at a child-care center between 24th of August and 18th of September 2020. A total of 52 persons in 19 household clusters were symptomatic in this outbreak investigation. Of all transmissions, 23 (46.9%) occurred in the child-care center, the rest occurring in households. We found a household attack rate of 36.5% (95% CI 27.3, 47.1%). Serial intervals were estimated as mean 2.5 ± SD1.45 days. The R0, using time-dependent methods during the growth phase of the outbreak (days 2 to 8) was 2.4 (95% CI 1.50, 3.50). The count of affected persons of a child-care center norovirus outbreak is approximately double the count of the total symptomatic staff and attending children. In the study setting, each symptomatic child-care attendee likely infected one other child-care attendee or staff and just over one household contact on average.
format	article
author	Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker
author_facet	Nicolas Roydon Smoll Arifuzzman Khan Jacina Walker Jamie McMahon Michael Kirk Gulam Khandaker
author_sort	Nicolas Roydon Smoll
title	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
title_short	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
title_full	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
title_fullStr	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
title_full_unstemmed	A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis
title_sort	norovirus gastroenteritis outbreak in an australian child-care center: a household-level analysis
publisher	Public Library of Science (PLoS)
publishDate	2021
url	https://doaj.org/article/f8ce4e93aae74e2a812c194080a6238f
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A norovirus gastroenteritis outbreak in an Australian child-care center: A household-level analysis

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