Three-dimensional scanless holographic optogenetics with temporal focusing (3D-SHOT)

Optogenetics, the optical stimulation of neurons, suffers from many technical challenges that limit the number of neurons that can be excited as well as their relative positions. Here, Pégard et al. develop a method to simultaneously stimulate an arbitrary number of neurons in 3D space with single n...

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Bibliographic Details
Main Authors: Nicolas C. Pégard, Alan R. Mardinly, Ian Antón Oldenburg, Savitha Sridharan, Laura Waller, Hillel Adesnik
Format: article
Language:EN
Published: Nature Portfolio 2017
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Online Access:https://doaj.org/article/f8cf7edd128c4d2ca3d12a7cae3f8952
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Summary:Optogenetics, the optical stimulation of neurons, suffers from many technical challenges that limit the number of neurons that can be excited as well as their relative positions. Here, Pégard et al. develop a method to simultaneously stimulate an arbitrary number of neurons in 3D space with single neuron resolution.