Effect of Caffeine on the retention and retrieval of memory in mice

Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, codin...

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Autores principales: A Arzi, AA Naderi
Formato: article
Lenguaje:EN
FA
Publicado: Babol University of Medical Sciences 2000
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Acceso en línea:https://doaj.org/article/f8d1bf3e283a410ea661034670a9553f
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spelling oai:doaj.org-article:f8d1bf3e283a410ea661034670a9553f2021-11-10T09:22:21ZEffect of Caffeine on the retention and retrieval of memory in mice1561-41072251-7170https://doaj.org/article/f8d1bf3e283a410ea661034670a9553f2000-10-01T00:00:00Zhttp://jbums.org/article-1-2889-en.htmlhttps://doaj.org/toc/1561-4107https://doaj.org/toc/2251-7170Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, coding and grouping, the mice were examined as follows: a) Test group that received electric shock and caffeine (5 mg/kg). B) Control group that received electric shock and saline (IP). C) Shame group that only received electric shock. The latency period for both retention and retrieval tests of memory in all three groups of mice were measured. Caffeine was injected immediately after an electric shock in the retention test of memory and 23,30´ hours after electric shock in the retrieval test of memory. Findings: Obtained results indicate that caffeine (5 mg/kg) reinforced retention of memory, but in comparison with control group, there was no significant difference and also it caused to reinforces retrieval of memory, but in comparison with control group, there was a significant difference. Conclusion: The results indicate that caffeine (5 mg/kg) has no effect on retention of memory, but it reinforces the retrieval of memory.A ArziAA NaderiBabol University of Medical Sciencesarticlecaffeinememoryelectric shockretention of memoryretrieval of memoryMedicineRMedicine (General)R5-920ENFAMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, Vol 2, Iss 4, Pp 12-16 (2000)
institution DOAJ
collection DOAJ
language EN
FA
topic caffeine
memory
electric shock
retention of memory
retrieval of memory
Medicine
R
Medicine (General)
R5-920
spellingShingle caffeine
memory
electric shock
retention of memory
retrieval of memory
Medicine
R
Medicine (General)
R5-920
A Arzi
AA Naderi
Effect of Caffeine on the retention and retrieval of memory in mice
description Objective: Caffeine consumption may reinforce and/or deteriorate memory and learning this is related to the dose of caffeine. The effect of caffeine on retention and retrieval of memory in mice, by using of passive avoidance learning was investigated. Methods: For this purpose after weighing, coding and grouping, the mice were examined as follows: a) Test group that received electric shock and caffeine (5 mg/kg). B) Control group that received electric shock and saline (IP). C) Shame group that only received electric shock. The latency period for both retention and retrieval tests of memory in all three groups of mice were measured. Caffeine was injected immediately after an electric shock in the retention test of memory and 23,30´ hours after electric shock in the retrieval test of memory. Findings: Obtained results indicate that caffeine (5 mg/kg) reinforced retention of memory, but in comparison with control group, there was no significant difference and also it caused to reinforces retrieval of memory, but in comparison with control group, there was a significant difference. Conclusion: The results indicate that caffeine (5 mg/kg) has no effect on retention of memory, but it reinforces the retrieval of memory.
format article
author A Arzi
AA Naderi
author_facet A Arzi
AA Naderi
author_sort A Arzi
title Effect of Caffeine on the retention and retrieval of memory in mice
title_short Effect of Caffeine on the retention and retrieval of memory in mice
title_full Effect of Caffeine on the retention and retrieval of memory in mice
title_fullStr Effect of Caffeine on the retention and retrieval of memory in mice
title_full_unstemmed Effect of Caffeine on the retention and retrieval of memory in mice
title_sort effect of caffeine on the retention and retrieval of memory in mice
publisher Babol University of Medical Sciences
publishDate 2000
url https://doaj.org/article/f8d1bf3e283a410ea661034670a9553f
work_keys_str_mv AT aarzi effectofcaffeineontheretentionandretrievalofmemoryinmice
AT aanaderi effectofcaffeineontheretentionandretrievalofmemoryinmice
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