Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study
Purpose: To conduct a multi-center analysis and assess the economic burden due to dry eye disease (DED) in China.Design: A retrospective and cross-sectional study.Methods: Patients (n = 598) with diagnosed DED were recruited from 3 eye centers (in central, southeast, and northeast China) from 1 Janu...
Guardado en:
| Autores principales: | , , , , , , , , , , , , , , , |
|---|---|
| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Frontiers Media S.A.
2021
|
| Materias: | |
| Acceso en línea: | https://doaj.org/article/f8d2003201784b08a1574830de28cbed |
| Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
| id |
oai:doaj.org-article:f8d2003201784b08a1574830de28cbed |
|---|---|
| record_format |
dspace |
| spelling |
oai:doaj.org-article:f8d2003201784b08a1574830de28cbed2021-12-01T21:45:11ZEstimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study2296-858X10.3389/fmed.2021.771352https://doaj.org/article/f8d2003201784b08a1574830de28cbed2021-12-01T00:00:00Zhttps://www.frontiersin.org/articles/10.3389/fmed.2021.771352/fullhttps://doaj.org/toc/2296-858XPurpose: To conduct a multi-center analysis and assess the economic burden due to dry eye disease (DED) in China.Design: A retrospective and cross-sectional study.Methods: Patients (n = 598) with diagnosed DED were recruited from 3 eye centers (in central, southeast, and northeast China) from 1 January 2018 to 31 December 2018. Data were collected regarding the examination, pharmacological therapy, and non-pharmacological therapy fees. Sub-group analyses were stratified by eye center, DED severity, types of DED, number of visits to physicians, and residential area. A logistic regression analysis was conducted to investigate the variables influencing total costs.Results: The per capita costs devoted to DED at the 3 centers were 422.6, 391.3, and 265.4 USD, respectively. The costs of non-pharmacological therapy accounted the largest part in three centers (75.6, 76.4, 76.5%, respectively). Patients with severe DED sustained the largest economic burden. Patients with mixed type of DED spent the most comparing to patients with either evaporative or aqueous-deficient types of DED. Patients spent more during the first visit compared with subsequent visits. Patients living in urban areas spent significantly more than did those living in rural areas (P = 0.001). The logistics regression analysis showed that total costs were significantly influenced by DED severity, number of visits to physicians, and area of residence (beta = 2.83, 0.83, 1.48; P < 0.0001).Conclusions: DED is a chronic ocular disease that timely non-cost counseling, early diagnosis, and efficacious treatment can reduce its economic burden on patients and the society.Wanju YangYanzhu LuoYanzhu LuoYanzhu LuoShangcao WuXiaoxia NiuYanshuang YanChen QiaoChen QiaoWei MingWei MingYing ZhangHaoyu WangHaoyu WangDan ChenDan ChenMengying QiMengying QiLan KeLan KeYing WangYing WangLiping LiLiping LiShaowei LiQingyan ZengQingyan ZengQingyan ZengQingyan ZengQingyan ZengFrontiers Media S.A.articledry eye diseaseburden of diseasecostsmulti-center analysisChinaMedicine (General)R5-920ENFrontiers in Medicine, Vol 8 (2021) |
| institution |
DOAJ |
| collection |
DOAJ |
| language |
EN |
| topic |
dry eye disease burden of disease costs multi-center analysis China Medicine (General) R5-920 |
| spellingShingle |
dry eye disease burden of disease costs multi-center analysis China Medicine (General) R5-920 Wanju Yang Yanzhu Luo Yanzhu Luo Yanzhu Luo Shangcao Wu Xiaoxia Niu Yanshuang Yan Chen Qiao Chen Qiao Wei Ming Wei Ming Ying Zhang Haoyu Wang Haoyu Wang Dan Chen Dan Chen Mengying Qi Mengying Qi Lan Ke Lan Ke Ying Wang Ying Wang Liping Li Liping Li Shaowei Li Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| description |
Purpose: To conduct a multi-center analysis and assess the economic burden due to dry eye disease (DED) in China.Design: A retrospective and cross-sectional study.Methods: Patients (n = 598) with diagnosed DED were recruited from 3 eye centers (in central, southeast, and northeast China) from 1 January 2018 to 31 December 2018. Data were collected regarding the examination, pharmacological therapy, and non-pharmacological therapy fees. Sub-group analyses were stratified by eye center, DED severity, types of DED, number of visits to physicians, and residential area. A logistic regression analysis was conducted to investigate the variables influencing total costs.Results: The per capita costs devoted to DED at the 3 centers were 422.6, 391.3, and 265.4 USD, respectively. The costs of non-pharmacological therapy accounted the largest part in three centers (75.6, 76.4, 76.5%, respectively). Patients with severe DED sustained the largest economic burden. Patients with mixed type of DED spent the most comparing to patients with either evaporative or aqueous-deficient types of DED. Patients spent more during the first visit compared with subsequent visits. Patients living in urban areas spent significantly more than did those living in rural areas (P = 0.001). The logistics regression analysis showed that total costs were significantly influenced by DED severity, number of visits to physicians, and area of residence (beta = 2.83, 0.83, 1.48; P < 0.0001).Conclusions: DED is a chronic ocular disease that timely non-cost counseling, early diagnosis, and efficacious treatment can reduce its economic burden on patients and the society. |
| format |
article |
| author |
Wanju Yang Yanzhu Luo Yanzhu Luo Yanzhu Luo Shangcao Wu Xiaoxia Niu Yanshuang Yan Chen Qiao Chen Qiao Wei Ming Wei Ming Ying Zhang Haoyu Wang Haoyu Wang Dan Chen Dan Chen Mengying Qi Mengying Qi Lan Ke Lan Ke Ying Wang Ying Wang Liping Li Liping Li Shaowei Li Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng |
| author_facet |
Wanju Yang Yanzhu Luo Yanzhu Luo Yanzhu Luo Shangcao Wu Xiaoxia Niu Yanshuang Yan Chen Qiao Chen Qiao Wei Ming Wei Ming Ying Zhang Haoyu Wang Haoyu Wang Dan Chen Dan Chen Mengying Qi Mengying Qi Lan Ke Lan Ke Ying Wang Ying Wang Liping Li Liping Li Shaowei Li Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng Qingyan Zeng |
| author_sort |
Wanju Yang |
| title |
Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| title_short |
Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| title_full |
Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| title_fullStr |
Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| title_full_unstemmed |
Estimated Annual Economic Burden of Dry Eye Disease Based on a Multi-Center Analysis in China: A Retrospective Study |
| title_sort |
estimated annual economic burden of dry eye disease based on a multi-center analysis in china: a retrospective study |
| publisher |
Frontiers Media S.A. |
| publishDate |
2021 |
| url |
https://doaj.org/article/f8d2003201784b08a1574830de28cbed |
| work_keys_str_mv |
AT wanjuyang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yanzhuluo estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yanzhuluo estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yanzhuluo estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT shangcaowu estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT xiaoxianiu estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yanshuangyan estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT chenqiao estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT chenqiao estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT weiming estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT weiming estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yingzhang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT haoyuwang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT haoyuwang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT danchen estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT danchen estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT mengyingqi estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT mengyingqi estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT lanke estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT lanke estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yingwang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT yingwang estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT lipingli estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT lipingli estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT shaoweili estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT qingyanzeng estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT qingyanzeng estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT qingyanzeng estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT qingyanzeng estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy AT qingyanzeng estimatedannualeconomicburdenofdryeyediseasebasedonamulticenteranalysisinchinaaretrospectivestudy |
| _version_ |
1718404199249608704 |