Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize

Abstract Southern leaf blight (SLB) and northern leaf blight (NLB) are the two major foliar diseases limiting maize production worldwide. Upon previous study with the nested association mapping (NAM) population, which consist of 5,000 recombinant inbred lines from 25 parents crossed with B73, we exp...

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Autores principales:	Yong-xiang Li, Lin Chen, Chunhui Li, Peter J. Bradbury, Yun-su Shi, Yanchun Song, Dengfeng Zhang, Zhiwu Zhang, Edward S. Buckler, Yu Li, Tianyu Wang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f8dac64118674b83a01b63dd2a53fb35
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spelling	oai:doaj.org-article:f8dac64118674b83a01b63dd2a53fb352021-12-02T16:08:02ZIncreased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize10.1038/s41598-018-25304-z2045-2322https://doaj.org/article/f8dac64118674b83a01b63dd2a53fb352018-05-01T00:00:00Zhttps://doi.org/10.1038/s41598-018-25304-zhttps://doaj.org/toc/2045-2322Abstract Southern leaf blight (SLB) and northern leaf blight (NLB) are the two major foliar diseases limiting maize production worldwide. Upon previous study with the nested association mapping (NAM) population, which consist of 5,000 recombinant inbred lines from 25 parents crossed with B73, we expanded the phenotyping environments from the United States (US) to China, and increased the marker densities from 1106 to 7386 SNPs for linkage mapping, and from 1.6 to 28.5 million markers for association mapping. We identified 49 SLB and 48 NLB resistance-related unique QTLs in linkage mapping, and multiple loci in association mapping with candidate genes involved in known plant disease-resistance pathways. Furthermore, an independent natural population with 282 diversified inbred lines were sequenced for four candidate genes selected based on their biological functions. Three of them demonstrated significant associations with disease resistance. These findings provided valuable resources for further implementations to develop varieties with superior resistance for NLB and SLB.Yong-xiang LiLin ChenChunhui LiPeter J. BradburyYun-su ShiYanchun SongDengfeng ZhangZhiwu ZhangEdward S. BucklerYu LiTianyu WangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yong-xiang Li Lin Chen Chunhui Li Peter J. Bradbury Yun-su Shi Yanchun Song Dengfeng Zhang Zhiwu Zhang Edward S. Buckler Yu Li Tianyu Wang Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
description	Abstract Southern leaf blight (SLB) and northern leaf blight (NLB) are the two major foliar diseases limiting maize production worldwide. Upon previous study with the nested association mapping (NAM) population, which consist of 5,000 recombinant inbred lines from 25 parents crossed with B73, we expanded the phenotyping environments from the United States (US) to China, and increased the marker densities from 1106 to 7386 SNPs for linkage mapping, and from 1.6 to 28.5 million markers for association mapping. We identified 49 SLB and 48 NLB resistance-related unique QTLs in linkage mapping, and multiple loci in association mapping with candidate genes involved in known plant disease-resistance pathways. Furthermore, an independent natural population with 282 diversified inbred lines were sequenced for four candidate genes selected based on their biological functions. Three of them demonstrated significant associations with disease resistance. These findings provided valuable resources for further implementations to develop varieties with superior resistance for NLB and SLB.
format	article
author	Yong-xiang Li Lin Chen Chunhui Li Peter J. Bradbury Yun-su Shi Yanchun Song Dengfeng Zhang Zhiwu Zhang Edward S. Buckler Yu Li Tianyu Wang
author_facet	Yong-xiang Li Lin Chen Chunhui Li Peter J. Bradbury Yun-su Shi Yanchun Song Dengfeng Zhang Zhiwu Zhang Edward S. Buckler Yu Li Tianyu Wang
author_sort	Yong-xiang Li
title	Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
title_short	Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
title_full	Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
title_fullStr	Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
title_full_unstemmed	Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
title_sort	increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f8dac64118674b83a01b63dd2a53fb35
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_version_	1718384693095694336

Increased experimental conditions and marker densities identified more genetic loci associated with southern and northern leaf blight resistance in maize

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