A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers

Currently, gut microbiome profiling largely relies on next-generation sequencing, which is slow and expensive. Here, the authors develop a low-cost, paper-based synthetic biology platform that allows species-specific quantification of bacterial mRNAs and clinically relevant host biomarkers.

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Autores principales:	Melissa K. Takahashi, Xiao Tan, Aaron J. Dy, Dana Braff, Reid T. Akana, Yoshikazu Furuta, Nina Donghia, Ashwin Ananthakrishnan, James J. Collins
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f8dae91102924721b1ee437d07c15480
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spelling	oai:doaj.org-article:f8dae91102924721b1ee437d07c154802021-12-02T14:38:48ZA low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers10.1038/s41467-018-05864-42041-1723https://doaj.org/article/f8dae91102924721b1ee437d07c154802018-08-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-05864-4https://doaj.org/toc/2041-1723Currently, gut microbiome profiling largely relies on next-generation sequencing, which is slow and expensive. Here, the authors develop a low-cost, paper-based synthetic biology platform that allows species-specific quantification of bacterial mRNAs and clinically relevant host biomarkers.Melissa K. TakahashiXiao TanAaron J. DyDana BraffReid T. AkanaYoshikazu FurutaNina DonghiaAshwin AnanthakrishnanJames J. CollinsNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Melissa K. Takahashi Xiao Tan Aaron J. Dy Dana Braff Reid T. Akana Yoshikazu Furuta Nina Donghia Ashwin Ananthakrishnan James J. Collins A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
description	Currently, gut microbiome profiling largely relies on next-generation sequencing, which is slow and expensive. Here, the authors develop a low-cost, paper-based synthetic biology platform that allows species-specific quantification of bacterial mRNAs and clinically relevant host biomarkers.
format	article
author	Melissa K. Takahashi Xiao Tan Aaron J. Dy Dana Braff Reid T. Akana Yoshikazu Furuta Nina Donghia Ashwin Ananthakrishnan James J. Collins
author_facet	Melissa K. Takahashi Xiao Tan Aaron J. Dy Dana Braff Reid T. Akana Yoshikazu Furuta Nina Donghia Ashwin Ananthakrishnan James J. Collins
author_sort	Melissa K. Takahashi
title	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
title_short	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
title_full	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
title_fullStr	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
title_full_unstemmed	A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
title_sort	low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f8dae91102924721b1ee437d07c15480
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A low-cost paper-based synthetic biology platform for analyzing gut microbiota and host biomarkers

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