DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death

DNA damage in circulating leukocytes measured with the comet assay may predict the risk of death

Abstract The comet assay or single cell gel electrophoresis, is the most common method used to measure strand breaks and a variety of other DNA lesions in human populations. To estimate the risk of overall mortality, mortality by cause, and cancer incidence associated to DNA damage, a cohort of 2,40...

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Main Authors: Stefano Bonassi, Marcello Ceppi, Peter Møller, Amaya Azqueta, Mirta Milić, Neri Monica, Gunnar Brunborg, Roger Godschalk, Gudrun Koppen, Sabine A. S. Langie, João Paulo Teixeira, Marco Bruzzone, Juliana Da Silva, Danieli Benedetti, Delia Cavallo, Cinzia Lucia Ursini, Lisa Giovannelli, Silvia Moretti, Patrizia Riso, Cristian Del Bo’, Patrizia Russo, Malgorzata Dobrzyńska, Irina A. Goroshinskaya, Ekaterina I. Surikova, Marta Staruchova, Magdalena Barančokova, Katarina Volkovova, Alena Kažimirova, Bozena Smolkova, Blanca Laffon, Vanessa Valdiglesias, Susana Pastor, Ricard Marcos, Alba Hernández, Goran Gajski, Biljana Spremo-Potparević, Lada Živković, Elisa Boutet-Robinet, Hervé Perdry, Pierre Lebailly, Carlos L. Perez, Nursen Basaran, Zsuzsanna Nemeth, Anna Safar, Maria Dusinska, Andrew Collins, for the hCOMET project
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
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Online Access:https://doaj.org/article/f8e27d7d62fb499faa7a487ea347b299
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