H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers

Electrophilic acylation of arenes is largely limited to electron rich systems, non-polar medium and often displays moderate selectivity. Here, the authors show a directed para-selective ketonisation of arenes, overriding electronic bias and structural congestion, and apply it to the synthesis of bio...

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Autores principales: Arun Maji, Amit Dahiya, Gang Lu, Trisha Bhattacharya, Massimo Brochetta, Giuseppe Zanoni, Peng Liu, Debabrata Maiti
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
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Acceso en línea:https://doaj.org/article/f8e52a1b27b94288a6c5af4e4c47e1b5
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spelling oai:doaj.org-article:f8e52a1b27b94288a6c5af4e4c47e1b52021-12-02T15:33:45ZH-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers10.1038/s41467-018-06018-22041-1723https://doaj.org/article/f8e52a1b27b94288a6c5af4e4c47e1b52018-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-06018-2https://doaj.org/toc/2041-1723Electrophilic acylation of arenes is largely limited to electron rich systems, non-polar medium and often displays moderate selectivity. Here, the authors show a directed para-selective ketonisation of arenes, overriding electronic bias and structural congestion, and apply it to the synthesis of bioactive compounds.Arun MajiAmit DahiyaGang LuTrisha BhattacharyaMassimo BrochettaGiuseppe ZanoniPeng LiuDebabrata MaitiNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Arun Maji
Amit Dahiya
Gang Lu
Trisha Bhattacharya
Massimo Brochetta
Giuseppe Zanoni
Peng Liu
Debabrata Maiti
H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
description Electrophilic acylation of arenes is largely limited to electron rich systems, non-polar medium and often displays moderate selectivity. Here, the authors show a directed para-selective ketonisation of arenes, overriding electronic bias and structural congestion, and apply it to the synthesis of bioactive compounds.
format article
author Arun Maji
Amit Dahiya
Gang Lu
Trisha Bhattacharya
Massimo Brochetta
Giuseppe Zanoni
Peng Liu
Debabrata Maiti
author_facet Arun Maji
Amit Dahiya
Gang Lu
Trisha Bhattacharya
Massimo Brochetta
Giuseppe Zanoni
Peng Liu
Debabrata Maiti
author_sort Arun Maji
title H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
title_short H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
title_full H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
title_fullStr H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
title_full_unstemmed H-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
title_sort h-bonded reusable template assisted para-selective ketonisation using soft electrophilic vinyl ethers
publisher Nature Portfolio
publishDate 2018
url https://doaj.org/article/f8e52a1b27b94288a6c5af4e4c47e1b5
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AT giuseppezanoni hbondedreusabletemplateassistedparaselectiveketonisationusingsoftelectrophilicvinylethers
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