Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations.

Non-linear interaction between physical activity and polygenic risk score of body mass index in Danish and Russian populations.

Body mass index (BMI) is a highly heritable polygenic trait. It is also affected by various environmental and behavioral risk factors. We used a BMI polygenic risk score (PRS) to study the interplay between the genetic and environmental factors defining BMI. First, we generated a BMI PRS that explai...

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Autores principales: Dmitrii Borisevich, Theresia M Schnurr, Line Engelbrechtsen, Alexander Rakitko, Lars Ängquist, Valery Ilinsky, Mette Aadahl, Niels Grarup, Oluf Pedersen, Thorkild I A Sørensen, Torben Hansen
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2021
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/f8f25c9ec0004da286e696ce993038ca
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