Carcinoma initiation via RB tumor suppressor inactivation: a versatile approach to epithelial subtype-dependent cancer initiation in diverse tissues.

Carcinomas arise in a complex microenvironment consisting of multiple distinct epithelial lineages surrounded by a variety of stromal cell types. Understanding cancer etiologies requires evaluating the relationship among cell types during disease initiation and through progression. Genetically engin...

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Autores principales: Yurong Song, Debra Gilbert, T Norene O'Sullivan, Chunyu Yang, Wenqi Pan, Alisan Fathalizadeh, Lucy Lu, Diana C Haines, Philip L Martin, Terry Van Dyke
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
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Acceso en línea:https://doaj.org/article/f8f8cf11eed944918839ab4509abf069
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