SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability

LncRNA TERRA forms RNA-DNA hybrids at telomere sites leading to telomere instability. Here the authors identify the RNA interacting factors NONO and SFPQ as proteins that interact with TERRA and telomere chromatin and reveal putative roles for these factors in telomere integry maintenance by interfe...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Eleonora Petti, Valentina Buemi, Antonina Zappone, Odessa Schillaci, Pamela Veneziano Broccia, Roberto Dinami, Silvia Matteoni, Roberta Benetti, Stefan Schoeftner
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2019
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d80
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f8f8d328c17a48d78dd6073e811e9d80
record_format	dspace
spelling	oai:doaj.org-article:f8f8d328c17a48d78dd6073e811e9d802021-12-02T14:39:01ZSFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability10.1038/s41467-019-08863-12041-1723https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d802019-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-08863-1https://doaj.org/toc/2041-1723LncRNA TERRA forms RNA-DNA hybrids at telomere sites leading to telomere instability. Here the authors identify the RNA interacting factors NONO and SFPQ as proteins that interact with TERRA and telomere chromatin and reveal putative roles for these factors in telomere integry maintenance by interfering with RNA:DNA hybrid formation.Eleonora PettiValentina BuemiAntonina ZapponeOdessa SchillaciPamela Veneziano BrocciaRoberto DinamiSilvia MatteoniRoberta BenettiStefan SchoeftnerNature PortfolioarticleScienceQENNature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Eleonora Petti Valentina Buemi Antonina Zappone Odessa Schillaci Pamela Veneziano Broccia Roberto Dinami Silvia Matteoni Roberta Benetti Stefan Schoeftner SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
description	LncRNA TERRA forms RNA-DNA hybrids at telomere sites leading to telomere instability. Here the authors identify the RNA interacting factors NONO and SFPQ as proteins that interact with TERRA and telomere chromatin and reveal putative roles for these factors in telomere integry maintenance by interfering with RNA:DNA hybrid formation.
format	article
author	Eleonora Petti Valentina Buemi Antonina Zappone Odessa Schillaci Pamela Veneziano Broccia Roberto Dinami Silvia Matteoni Roberta Benetti Stefan Schoeftner
author_facet	Eleonora Petti Valentina Buemi Antonina Zappone Odessa Schillaci Pamela Veneziano Broccia Roberto Dinami Silvia Matteoni Roberta Benetti Stefan Schoeftner
author_sort	Eleonora Petti
title	SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
title_short	SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
title_full	SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
title_fullStr	SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
title_full_unstemmed	SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability
title_sort	sfpq and nono suppress rna:dna-hybrid-related telomere instability
publisher	Nature Portfolio
publishDate	2019
url	https://doaj.org/article/f8f8d328c17a48d78dd6073e811e9d80
work_keys_str_mv	AT eleonorapetti sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT valentinabuemi sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT antoninazappone sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT odessaschillaci sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT pamelavenezianobroccia sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT robertodinami sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT silviamatteoni sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT robertabenetti sfpqandnonosuppressrnadnahybridrelatedtelomereinstability AT stefanschoeftner sfpqandnonosuppressrnadnahybridrelatedtelomereinstability
_version_	1718390808320671744

SFPQ and NONO suppress RNA:DNA-hybrid-related telomere instability

Ejemplares similares