Lifestyle interventions for the treatment of non-alcoholic fatty liver disease

V Bradford, JF Dillon, MH Miller Gut Group, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland Abstract: The burden of non-alcoholic fatty liver disease (NAFLD) worldwide is a significant clinical and public health issue, affecting approximate...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Bradford V, Dillon JF, Miller MH
Formato:	article
Lenguaje:	EN
Publicado:	Dove Medical Press 2013
Materias:	Diseases of the digestive system. Gastroenterology RC799-869
Acceso en línea:	https://doaj.org/article/f8fc2539dda14a3f809e847dd43a9747
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f8fc2539dda14a3f809e847dd43a9747
record_format	dspace
spelling	oai:doaj.org-article:f8fc2539dda14a3f809e847dd43a97472021-12-02T01:10:20ZLifestyle interventions for the treatment of non-alcoholic fatty liver disease1179-1535https://doaj.org/article/f8fc2539dda14a3f809e847dd43a97472013-12-01T00:00:00Zhttp://www.dovepress.com/lifestyle-interventions-for-the-treatment-of-non-alcoholic-fatty-liver-a15261https://doaj.org/toc/1179-1535 V Bradford, JF Dillon, MH Miller Gut Group, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland Abstract: The burden of non-alcoholic fatty liver disease (NAFLD) worldwide is a significant clinical and public health issue, affecting approximately one third of the Western population. This review assesses the effect and impact lifestyle interventions have on the treatment of this common condition. We review studies comparing the effect of calorie restriction and exercise programs, as well as comparison of lifestyle intervention with pharmaceutical intervention. Both calorie restriction and exercise programs are shown to be beneficial in improving features of metabolic syndrome and surrogate markers of NAFLD. The paucity of studies using histological improvement hinders the ability to conclude a benefit on improvement of histological NAFLD, although this is shown in a small number of studies. There is a need to extend the intervention period to show a sustained improvement with intervention as most studies have a follow up period of 12 months of less. Keywords: NAFLD, lifestyle intervention, exercise, dietBradford VDillon JFMiller MHDove Medical PressarticleDiseases of the digestive system. GastroenterologyRC799-869ENHepatic Medicine: Evidence and Research, Vol 2014, Iss default, Pp 1-10 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the digestive system. Gastroenterology RC799-869
spellingShingle	Diseases of the digestive system. Gastroenterology RC799-869 Bradford V Dillon JF Miller MH Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
description	V Bradford, JF Dillon, MH Miller Gut Group, Medical Research Institute, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland Abstract: The burden of non-alcoholic fatty liver disease (NAFLD) worldwide is a significant clinical and public health issue, affecting approximately one third of the Western population. This review assesses the effect and impact lifestyle interventions have on the treatment of this common condition. We review studies comparing the effect of calorie restriction and exercise programs, as well as comparison of lifestyle intervention with pharmaceutical intervention. Both calorie restriction and exercise programs are shown to be beneficial in improving features of metabolic syndrome and surrogate markers of NAFLD. The paucity of studies using histological improvement hinders the ability to conclude a benefit on improvement of histological NAFLD, although this is shown in a small number of studies. There is a need to extend the intervention period to show a sustained improvement with intervention as most studies have a follow up period of 12 months of less. Keywords: NAFLD, lifestyle intervention, exercise, diet
format	article
author	Bradford V Dillon JF Miller MH
author_facet	Bradford V Dillon JF Miller MH
author_sort	Bradford V
title	Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
title_short	Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
title_full	Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
title_fullStr	Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
title_full_unstemmed	Lifestyle interventions for the treatment of non-alcoholic fatty liver disease
title_sort	lifestyle interventions for the treatment of non-alcoholic fatty liver disease
publisher	Dove Medical Press
publishDate	2013
url	https://doaj.org/article/f8fc2539dda14a3f809e847dd43a9747
work_keys_str_mv	AT bradfordv lifestyleinterventionsforthetreatmentofnonalcoholicfattyliverdisease AT dillonjf lifestyleinterventionsforthetreatmentofnonalcoholicfattyliverdisease AT millermh lifestyleinterventionsforthetreatmentofnonalcoholicfattyliverdisease
_version_	1718403293645897728

Lifestyle interventions for the treatment of non-alcoholic fatty liver disease

Ejemplares similares