Clinically translatable quantitative molecular photoacoustic imaging with liposome-encapsulated ICG J-aggregates

Photoacoustic imaging is limited by a lack of contrast agents which can enable combined molecular and physiological imaging at depth. Here the authors address these limitations by developing and validating a contrast agent based on targeted liposomes loaded with J-aggregated indocyanine green dye.

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Auteurs principaux: Cayla A. Wood, Sangheon Han, Chang Soo Kim, Yunfei Wen, Diego R. T. Sampaio, Justin T. Harris, Kimberly A. Homan, Jody L. Swain, Stanislav Y. Emelianov, Anil K. Sood, Jason R. Cook, Konstantin V. Sokolov, Richard R. Bouchard
Format: article
Langue:EN
Publié: Nature Portfolio 2021
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Accès en ligne:https://doaj.org/article/f8fd07c06f6e4cb5a601b70fceb08dc6
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Résumé:Photoacoustic imaging is limited by a lack of contrast agents which can enable combined molecular and physiological imaging at depth. Here the authors address these limitations by developing and validating a contrast agent based on targeted liposomes loaded with J-aggregated indocyanine green dye.