TET-mediated epimutagenesis of the Arabidopsis thaliana methylome

In plants, variation in DNA methylation can influence agronomically important traits. Here the authors show that expression of a human Ten-eleven translocation enzyme can generate heritable hypomethylation alleles in Arabidopsis, providing a novel method to manipulate DNA methylation for breeding an...

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Autores principales:	Lexiang Ji, William T. Jordan, Xiuling Shi, Lulu Hu, Chuan He, Robert J. Schmitz
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2018
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9098522e5324f8bacfcf69d740b2529
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spelling	oai:doaj.org-article:f9098522e5324f8bacfcf69d740b25292021-12-02T14:40:54ZTET-mediated epimutagenesis of the Arabidopsis thaliana methylome10.1038/s41467-018-03289-72041-1723https://doaj.org/article/f9098522e5324f8bacfcf69d740b25292018-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-018-03289-7https://doaj.org/toc/2041-1723In plants, variation in DNA methylation can influence agronomically important traits. Here the authors show that expression of a human Ten-eleven translocation enzyme can generate heritable hypomethylation alleles in Arabidopsis, providing a novel method to manipulate DNA methylation for breeding and research purposes.Lexiang JiWilliam T. JordanXiuling ShiLulu HuChuan HeRobert J. SchmitzNature PortfolioarticleScienceQENNature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Lexiang Ji William T. Jordan Xiuling Shi Lulu Hu Chuan He Robert J. Schmitz TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
description	In plants, variation in DNA methylation can influence agronomically important traits. Here the authors show that expression of a human Ten-eleven translocation enzyme can generate heritable hypomethylation alleles in Arabidopsis, providing a novel method to manipulate DNA methylation for breeding and research purposes.
format	article
author	Lexiang Ji William T. Jordan Xiuling Shi Lulu Hu Chuan He Robert J. Schmitz
author_facet	Lexiang Ji William T. Jordan Xiuling Shi Lulu Hu Chuan He Robert J. Schmitz
author_sort	Lexiang Ji
title	TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
title_short	TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
title_full	TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
title_fullStr	TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
title_full_unstemmed	TET-mediated epimutagenesis of the Arabidopsis thaliana methylome
title_sort	tet-mediated epimutagenesis of the arabidopsis thaliana methylome
publisher	Nature Portfolio
publishDate	2018
url	https://doaj.org/article/f9098522e5324f8bacfcf69d740b2529
work_keys_str_mv	AT lexiangji tetmediatedepimutagenesisofthearabidopsisthalianamethylome AT williamtjordan tetmediatedepimutagenesisofthearabidopsisthalianamethylome AT xiulingshi tetmediatedepimutagenesisofthearabidopsisthalianamethylome AT luluhu tetmediatedepimutagenesisofthearabidopsisthalianamethylome AT chuanhe tetmediatedepimutagenesisofthearabidopsisthalianamethylome AT robertjschmitz tetmediatedepimutagenesisofthearabidopsisthalianamethylome
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TET-mediated epimutagenesis of the Arabidopsis thaliana methylome

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