Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA.
Faithful inheritance of mitochondrial DNA (mtDNA) is crucial for cellular respiration/oxidative phosphorylation and mitochondrial membrane potential. However, how mtDNA is transmitted to progeny is not fully understood. We utilized hypersuppressive mtDNA, a class of respiratory deficient Saccharomyc...
Guardado en:
Autores principales: | Daniel Corbi, Angelika Amon |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Public Library of Science (PLoS)
2021
|
Materias: | |
Acceso en línea: | https://doaj.org/article/f909f2d7178f451eac63b3dc87e1101b |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Increased mitochondrial protein import and cardiolipin remodelling upon early mtUPR.
por: Daniel Poveda-Huertes, et al.
Publicado: (2021) -
Mechanism of suppression of chromosomal instability by DNA polymerase POLQ.
por: Matthew J Yousefzadeh, et al.
Publicado: (2014) -
Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
por: Ignacio Soriano, et al.
Publicado: (2021) -
A reversible histone H3 acetylation cooperates with mismatch repair and replicative polymerases in maintaining genome stability.
por: Lyudmila Y Kadyrova, et al.
Publicado: (2013) -
Unexpected role for Helicobacter pylori DNA polymerase I as a source of genetic variability.
por: María-Victoria García-Ortíz, et al.
Publicado: (2011)