HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

HDAC6: A Novel Histone Deacetylase Implicated in Pulmonary Arterial Hypertension

Abstract Pulmonary arterial hypertension (PAH) is a vascular remodeling disease with limited therapeutic options. Although exposed to stressful conditions, pulmonary artery (PA) smooth muscle cells (PASMCs) exhibit a “cancer-like” pro-proliferative and anti-apoptotic phenotype. HDAC6 is a cytoplasmi...

Full description

Saved in:
Bibliographic Details
Main Authors: Olivier Boucherat, Sophie Chabot, Roxane Paulin, Isabelle Trinh, Alice Bourgeois, François Potus, Marie-Claude Lampron, Caroline Lambert, Sandra Breuils-Bonnet, Valérie Nadeau, Renée Paradis, Elena A. Goncharova, Steeve Provencher, Sébastien Bonnet
Format: article
Language:EN
Published: Nature Portfolio 2017
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/f90d5634c64f49ecb27fef8c14550b2f
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

https://doaj.org/article/f90d5634c64f49ecb27fef8c14550b2f

Similar Items