Dissecting the role of PfAP2-G in malaria gametocytogenesis

The transcription factor PfAP2-G is a key determinant of sexual commitment in Plasmodium falciparum. Here, Josling et al. define the transcriptional regulatory network of PfAP2-G by identifying its DNA binding sites genome-wide, which vary depending on the route of sexual conversion and rely on inte...

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Autores principales:	Gabrielle A. Josling, Timothy J. Russell, Jarrett Venezia, Lindsey Orchard, Riëtte van Biljon, Heather J. Painter, Manuel Llinás
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f90ecece4cf04d5aadfa0d28ad654ec5
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spelling	oai:doaj.org-article:f90ecece4cf04d5aadfa0d28ad654ec52021-12-02T17:32:14ZDissecting the role of PfAP2-G in malaria gametocytogenesis10.1038/s41467-020-15026-02041-1723https://doaj.org/article/f90ecece4cf04d5aadfa0d28ad654ec52020-03-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-15026-0https://doaj.org/toc/2041-1723The transcription factor PfAP2-G is a key determinant of sexual commitment in Plasmodium falciparum. Here, Josling et al. define the transcriptional regulatory network of PfAP2-G by identifying its DNA binding sites genome-wide, which vary depending on the route of sexual conversion and rely on interactions with the PfAP2-I transcription factor.Gabrielle A. JoslingTimothy J. RussellJarrett VeneziaLindsey OrchardRiëtte van BiljonHeather J. PainterManuel LlinásNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gabrielle A. Josling Timothy J. Russell Jarrett Venezia Lindsey Orchard Riëtte van Biljon Heather J. Painter Manuel Llinás Dissecting the role of PfAP2-G in malaria gametocytogenesis
description	The transcription factor PfAP2-G is a key determinant of sexual commitment in Plasmodium falciparum. Here, Josling et al. define the transcriptional regulatory network of PfAP2-G by identifying its DNA binding sites genome-wide, which vary depending on the route of sexual conversion and rely on interactions with the PfAP2-I transcription factor.
format	article
author	Gabrielle A. Josling Timothy J. Russell Jarrett Venezia Lindsey Orchard Riëtte van Biljon Heather J. Painter Manuel Llinás
author_facet	Gabrielle A. Josling Timothy J. Russell Jarrett Venezia Lindsey Orchard Riëtte van Biljon Heather J. Painter Manuel Llinás
author_sort	Gabrielle A. Josling
title	Dissecting the role of PfAP2-G in malaria gametocytogenesis
title_short	Dissecting the role of PfAP2-G in malaria gametocytogenesis
title_full	Dissecting the role of PfAP2-G in malaria gametocytogenesis
title_fullStr	Dissecting the role of PfAP2-G in malaria gametocytogenesis
title_full_unstemmed	Dissecting the role of PfAP2-G in malaria gametocytogenesis
title_sort	dissecting the role of pfap2-g in malaria gametocytogenesis
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f90ecece4cf04d5aadfa0d28ad654ec5
work_keys_str_mv	AT gabrielleajosling dissectingtheroleofpfap2ginmalariagametocytogenesis AT timothyjrussell dissectingtheroleofpfap2ginmalariagametocytogenesis AT jarrettvenezia dissectingtheroleofpfap2ginmalariagametocytogenesis AT lindseyorchard dissectingtheroleofpfap2ginmalariagametocytogenesis AT riettevanbiljon dissectingtheroleofpfap2ginmalariagametocytogenesis AT heatherjpainter dissectingtheroleofpfap2ginmalariagametocytogenesis AT manuelllinas dissectingtheroleofpfap2ginmalariagametocytogenesis
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Dissecting the role of PfAP2-G in malaria gametocytogenesis

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