Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.
Gliotoxin, and other related molecules, are encoded by multi-gene clusters and biosynthesized by fungi using non-ribosomal biosynthetic mechanisms. Almost universally described in terms of its toxicity towards mammalian cells, gliotoxin has come to be considered as a component of the virulence arsen...
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Auteurs principaux: | Markus Schrettl, Stephen Carberry, Kevin Kavanagh, Hubertus Haas, Gary W Jones, Jennifer O'Brien, Aine Nolan, John Stephens, Orla Fenelon, Sean Doyle |
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Format: | article |
Langue: | EN |
Publié: |
Public Library of Science (PLoS)
2010
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Accès en ligne: | https://doaj.org/article/f913a2e92bf04bbd8b958d59f502fd37 |
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