Self-protection against gliotoxin--a component of the gliotoxin biosynthetic cluster, GliT, completely protects Aspergillus fumigatus against exogenous gliotoxin.
Gliotoxin, and other related molecules, are encoded by multi-gene clusters and biosynthesized by fungi using non-ribosomal biosynthetic mechanisms. Almost universally described in terms of its toxicity towards mammalian cells, gliotoxin has come to be considered as a component of the virulence arsen...
Saved in:
Main Authors: | Markus Schrettl, Stephen Carberry, Kevin Kavanagh, Hubertus Haas, Gary W Jones, Jennifer O'Brien, Aine Nolan, John Stephens, Orla Fenelon, Sean Doyle |
---|---|
Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2010
|
Subjects: | |
Online Access: | https://doaj.org/article/f913a2e92bf04bbd8b958d59f502fd37 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Induction of gliotoxin secretion in Aspergillus fumigatus by bacteria-associated molecules.
by: K Stefan Svahn, et al.
Published: (2014) -
Production, stability and degradation of Trichoderma gliotoxin in growth medium, irrigation water and agricultural soil
by: R. Jayalakshmi, et al.
Published: (2021) -
Identification of a novel anoikis signalling pathway using the fungal virulence factor gliotoxin
by: Florian Haun, et al.
Published: (2018) -
Gliotoxin Suppresses Macrophage Immune Function by Subverting Phosphatidylinositol 3,4,5-Trisphosphate Homeostasis
by: Daniel Schlam, et al.
Published: (2016) -
Gliotoxin, a Known Virulence Factor in the Major Human Pathogen <named-content content-type="genus-species">Aspergillus fumigatus</named-content>, Is Also Biosynthesized by Its Nonpathogenic Relative <italic toggle="yes">Aspergillus fischeri</italic>
by: Sonja L. Knowles, et al.
Published: (2020)