High-fat and high-cholesterol diet decreases phosphorylated inositol-requiring kinase-1 and inhibits autophagy process in rat liver
Abstract Precise molecular pathways involved in the progression of non-alcoholic steatohepatitis (NASH) remain to be elucidated. As Mallory–Denk bodies were occasionally observed in the enlarged hepatocytes in NASH model rat (SHRSP5/Dmcr) fed high-fat and high-cholesterol (HFC) diet, we aimed to cla...
Enregistré dans:
Auteurs principaux: | Hisao Naito, Yuki Yoshikawa-Bando, Yuan Yuan, Sayuki Hashimoto, Kazuya Kitamori, Hiroshi Yatsuya, Tamie Nakajima |
---|---|
Format: | article |
Langue: | EN |
Publié: |
Nature Portfolio
2019
|
Sujets: | |
Accès en ligne: | https://doaj.org/article/f91c6d4f598d4f9c8d009ffc735a237d |
Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
Documents similaires
-
Decreased high density lipoprotein cholesterol is an independent predictor for persistent organ failure, pancreatic necrosis and mortality in acute pancreatitis
par: Yushun Zhang, et autres
Publié: (2017) -
Modulation of cytosolic calcium signaling by protein kinase A-mediated phosphorylation of inositol 1,4,5-trisphosphate receptors
par: STRAUB,STEPHEN V, et autres
Publié: (2004) -
Phosphorylation regulates the binding of autophagy receptors to FIP200 Claw domain for selective autophagy initiation
par: Zixuan Zhou, et autres
Publié: (2021) -
Decreased Triglyceride and Increased Serum Lipoprotein Lipase Levels Are Correlated to Increased High-Density Lipoprotein-Cholesterol Levels after Laparoscopic Sleeve Gastrectomy
par: Masahiro Ohira, et autres
Publié: (2021) -
Accumulation of cholesterol suppresses oxidative phosphorylation and altered responses to inflammatory stimuli of macrophages
par: Yi-Chou Chiu, et autres
Publié: (2021)