Non-invasive Diagnostics of Liver Fibrosis

Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide varie...

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Autores principales: Mihaylov R., Pencheva B., Stoeva D., Ruseva A.
Formato: article
Lenguaje:EN
Publicado: Sciendo 2017
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Acceso en línea:https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef4
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spelling oai:doaj.org-article:f91e61c166f8441b80e6843f6ac7aef42021-12-02T19:11:12ZNon-invasive Diagnostics of Liver Fibrosis0324-175010.1515/amb-2017-0009https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef42017-05-01T00:00:00Zhttps://doi.org/10.1515/amb-2017-0009https://doaj.org/toc/0324-1750Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.Mihaylov R.Pencheva B.Stoeva D.Ruseva A.Sciendoarticleliver fibrosisliver biopsyalcoholic liver diseasenon-alcoholic fatty liver diseasechronic viral hepatitis bchronic viral hepatitis cMedicineRENActa Medica Bulgarica, Vol 44, Iss 1, Pp 50-56 (2017)
institution DOAJ
collection DOAJ
language EN
topic liver fibrosis
liver biopsy
alcoholic liver disease
non-alcoholic fatty liver disease
chronic viral hepatitis b
chronic viral hepatitis c
Medicine
R
spellingShingle liver fibrosis
liver biopsy
alcoholic liver disease
non-alcoholic fatty liver disease
chronic viral hepatitis b
chronic viral hepatitis c
Medicine
R
Mihaylov R.
Pencheva B.
Stoeva D.
Ruseva A.
Non-invasive Diagnostics of Liver Fibrosis
description Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.
format article
author Mihaylov R.
Pencheva B.
Stoeva D.
Ruseva A.
author_facet Mihaylov R.
Pencheva B.
Stoeva D.
Ruseva A.
author_sort Mihaylov R.
title Non-invasive Diagnostics of Liver Fibrosis
title_short Non-invasive Diagnostics of Liver Fibrosis
title_full Non-invasive Diagnostics of Liver Fibrosis
title_fullStr Non-invasive Diagnostics of Liver Fibrosis
title_full_unstemmed Non-invasive Diagnostics of Liver Fibrosis
title_sort non-invasive diagnostics of liver fibrosis
publisher Sciendo
publishDate 2017
url https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef4
work_keys_str_mv AT mihaylovr noninvasivediagnosticsofliverfibrosis
AT penchevab noninvasivediagnosticsofliverfibrosis
AT stoevad noninvasivediagnosticsofliverfibrosis
AT rusevaa noninvasivediagnosticsofliverfibrosis
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