Non-invasive Diagnostics of Liver Fibrosis

Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide varie...

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Main Authors:	Mihaylov R., Pencheva B., Stoeva D., Ruseva A.
Format:	article
Language:	EN
Published:	Sciendo 2017
Subjects:	liver fibrosis liver biopsy alcoholic liver disease non-alcoholic fatty liver disease chronic viral hepatitis b chronic viral hepatitis c Medicine R
Online Access:	https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef4
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spelling	oai:doaj.org-article:f91e61c166f8441b80e6843f6ac7aef42021-12-02T19:11:12ZNon-invasive Diagnostics of Liver Fibrosis0324-175010.1515/amb-2017-0009https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef42017-05-01T00:00:00Zhttps://doi.org/10.1515/amb-2017-0009https://doaj.org/toc/0324-1750Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.Mihaylov R.Pencheva B.Stoeva D.Ruseva A.Sciendoarticleliver fibrosisliver biopsyalcoholic liver diseasenon-alcoholic fatty liver diseasechronic viral hepatitis bchronic viral hepatitis cMedicineRENActa Medica Bulgarica, Vol 44, Iss 1, Pp 50-56 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	liver fibrosis liver biopsy alcoholic liver disease non-alcoholic fatty liver disease chronic viral hepatitis b chronic viral hepatitis c Medicine R
spellingShingle	liver fibrosis liver biopsy alcoholic liver disease non-alcoholic fatty liver disease chronic viral hepatitis b chronic viral hepatitis c Medicine R Mihaylov R. Pencheva B. Stoeva D. Ruseva A. Non-invasive Diagnostics of Liver Fibrosis
description	Detecting new units of pathogenesis in the liver fibrosis due to alcoholism, chronic viral Hepatitis B and C, non-alcoholic fatty liver disease (NAFLD), autoimmune, parasitic and metabolic diseases and other, reveals perspective for new non-invasive serum biomarkers. In fibrosis, from the wide variety of markers enzymes, proteins and cytokines are mainly used. While direct biomarkers reflect the stage of fibrosis and fibrinogenesis, indirect markers allow assessment of the general liver functions. The combination of direct and indirect markers increases the diagnostic reliability and therefore these panels and indices are investigated quite intensively in recent years in order to decrease the number of liver biopsies without completely replace it, which is still regarded as the reference method.
format	article
author	Mihaylov R. Pencheva B. Stoeva D. Ruseva A.
author_facet	Mihaylov R. Pencheva B. Stoeva D. Ruseva A.
author_sort	Mihaylov R.
title	Non-invasive Diagnostics of Liver Fibrosis
title_short	Non-invasive Diagnostics of Liver Fibrosis
title_full	Non-invasive Diagnostics of Liver Fibrosis
title_fullStr	Non-invasive Diagnostics of Liver Fibrosis
title_full_unstemmed	Non-invasive Diagnostics of Liver Fibrosis
title_sort	non-invasive diagnostics of liver fibrosis
publisher	Sciendo
publishDate	2017
url	https://doaj.org/article/f91e61c166f8441b80e6843f6ac7aef4
work_keys_str_mv	AT mihaylovr noninvasivediagnosticsofliverfibrosis AT penchevab noninvasivediagnosticsofliverfibrosis AT stoevad noninvasivediagnosticsofliverfibrosis AT rusevaa noninvasivediagnosticsofliverfibrosis
_version_	1718377125040357376

Non-invasive Diagnostics of Liver Fibrosis

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