Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

Abstract The associations of single nucleotide polymorphisms (SNPs) in PLA2R1 and HLA-DQA1, as well as HLA-DRB1*15:01-DQB1*06:02 haplotype with idiopathic membranous nephropathy (IMN) is well known. However, the primary associations of these loci still need to be determined. We used Japanese-specifi...

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Auteurs principaux:	Khun Zaw Latt, Kenjiro Honda, Myo Thiri, Yuki Hitomi, Yosuke Omae, Hiromi Sawai, Yosuke Kawai, Shunsuke Teraguchi, Kazuko Ueno, Masao Nagasaki, Akihiko Mabuchi, Hajime Kaga, Atsushi Komatsuda, Katsushi Tokunaga, Eisei Noiri
Format:	article
Langue:	EN
Publié:	Nature Portfolio 2018
Sujets:	Idiopathic Membranous Nephropathy Phospholipase A2 Receptor (PLA2R) Missense SNPs Single Nucleotide Polymorphisms (SNPs) Additional Risk Allele Medicine R Science Q
Accès en ligne:	https://doaj.org/article/f927285d7e104cbc8d6e45b143eb5502
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Identification of a two-SNP PLA2R1 Haplotype and HLA-DRB1 Alleles as Primary Risk Associations in Idiopathic Membranous Nephropathy

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