The oncological relevance of fragile sites in cancer

In this Perspective, Simpson, Pye, and Whitaker discuss recent research identifying structural genomic variants in human cancers with a particular focus on deletions and duplications at genomic fragile sites. They argue that tumours with predominantly fragile site structural variants represent a dis...

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Autores principales: Benjamin S. Simpson, Hayley Pye, Hayley C. Whitaker
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f92db571ff224759973b72f56540a4ab
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