Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances

Background: The effect of the antimicrobial agents benzalkonium chloride (BC) and cetylpyridinium chloride (CPC) on the restorative glass ionomer tooth cement (GIC) Fuji IX was investigated. Aim of the study: The aim of the study was to determine whether the addition of antimicrobial compounds impai...

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Autores principales:	Dimkov Aleksandar G., Nicholson John W., Gjorgievska Elizabeta S.
Formato:	article
Lenguaje:	EN SR
Publicado:	Medicinski fakultet i Klinika za stomatologiju, Niš 2021
Materias:	benzalkonium chloride cetylpyridium chloride controlled release diffusion glass-ionomer Dentistry RK1-715
Acceso en línea:	https://doaj.org/article/f93090f77ff947b9b2ecaadaad501b06
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spelling	oai:doaj.org-article:f93090f77ff947b9b2ecaadaad501b062021-12-05T18:00:43ZPhysical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances0352-52521820-120210.5937/asn2183125Dhttps://doaj.org/article/f93090f77ff947b9b2ecaadaad501b062021-01-01T00:00:00Zhttps://scindeks-clanci.ceon.rs/data/pdf/0352-5252/2021/0352-52522183125D.pdfhttps://doaj.org/toc/0352-5252https://doaj.org/toc/1820-1202Background: The effect of the antimicrobial agents benzalkonium chloride (BC) and cetylpyridinium chloride (CPC) on the restorative glass ionomer tooth cement (GIC) Fuji IX was investigated. Aim of the study: The aim of the study was to determine whether the addition of antimicrobial compounds impairs the physical and mechanical properties of the commercial GIC Fuji IX. Materials and Methods: The concentrations of 1%, 2% and 3% of antimicrobial agentsBC and CPC, by weight of the cement, were added during the mixing phase and different effects were studied. In most samples, there was a slight change in setting time. Samples with 4 mm diameter and 6 mm height were used to measure compressive strength and release. The release of antimicrobial compounds was analysed by UV-visible spectrophotometry at a wavelength of 259 nm for CPC and 214 nm for BC, in deionized water. Results: The obtained results showed that the release takes place through the diffusion mechanism in the first 2-3 hours, and the diffusion coefficients vary depending on the concentration. The values range is from 1.97 x 10-14 -1.78 x 10-12 m2 s-1. Release of antimicrobial compound had ceased after seven days, with total release representing between 2.15 and 4.84% of the initial additive loading. Conclusion: Both compounds have minor effect on the setting time of the GIC. The reduction of compressive strength is not statistically significant. CPC containing cements (1 and 2%), were statistically significantly weaker, than those containing BC (p<0.05).Both antimicrobial compounds have shown constant release from the GIC with values which are directly proportional both to the time and to the concentration.Dimkov Aleksandar G.Nicholson John W.Gjorgievska Elizabeta S.Medicinski fakultet i Klinika za stomatologiju, Nišarticlebenzalkonium chloridecetylpyridium chloridecontrolled releasediffusionglass-ionomerDentistryRK1-715ENSRActa Stomatologica Naissi, Vol 37, Iss 83, Pp 2125-2135 (2021)
institution	DOAJ
collection	DOAJ
language	EN SR
topic	benzalkonium chloride cetylpyridium chloride controlled release diffusion glass-ionomer Dentistry RK1-715
spellingShingle	benzalkonium chloride cetylpyridium chloride controlled release diffusion glass-ionomer Dentistry RK1-715 Dimkov Aleksandar G. Nicholson John W. Gjorgievska Elizabeta S. Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
description	Background: The effect of the antimicrobial agents benzalkonium chloride (BC) and cetylpyridinium chloride (CPC) on the restorative glass ionomer tooth cement (GIC) Fuji IX was investigated. Aim of the study: The aim of the study was to determine whether the addition of antimicrobial compounds impairs the physical and mechanical properties of the commercial GIC Fuji IX. Materials and Methods: The concentrations of 1%, 2% and 3% of antimicrobial agentsBC and CPC, by weight of the cement, were added during the mixing phase and different effects were studied. In most samples, there was a slight change in setting time. Samples with 4 mm diameter and 6 mm height were used to measure compressive strength and release. The release of antimicrobial compounds was analysed by UV-visible spectrophotometry at a wavelength of 259 nm for CPC and 214 nm for BC, in deionized water. Results: The obtained results showed that the release takes place through the diffusion mechanism in the first 2-3 hours, and the diffusion coefficients vary depending on the concentration. The values range is from 1.97 x 10-14 -1.78 x 10-12 m2 s-1. Release of antimicrobial compound had ceased after seven days, with total release representing between 2.15 and 4.84% of the initial additive loading. Conclusion: Both compounds have minor effect on the setting time of the GIC. The reduction of compressive strength is not statistically significant. CPC containing cements (1 and 2%), were statistically significantly weaker, than those containing BC (p<0.05).Both antimicrobial compounds have shown constant release from the GIC with values which are directly proportional both to the time and to the concentration.
format	article
author	Dimkov Aleksandar G. Nicholson John W. Gjorgievska Elizabeta S.
author_facet	Dimkov Aleksandar G. Nicholson John W. Gjorgievska Elizabeta S.
author_sort	Dimkov Aleksandar G.
title	Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
title_short	Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
title_full	Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
title_fullStr	Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
title_full_unstemmed	Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
title_sort	physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances
publisher	Medicinski fakultet i Klinika za stomatologiju, Niš
publishDate	2021
url	https://doaj.org/article/f93090f77ff947b9b2ecaadaad501b06
work_keys_str_mv	AT dimkovaleksandarg physicalandmechanicalpropertiesofconventionalglassionomercementincorporatedwithcationicsubstances AT nicholsonjohnw physicalandmechanicalpropertiesofconventionalglassionomercementincorporatedwithcationicsubstances AT gjorgievskaelizabetas physicalandmechanicalpropertiesofconventionalglassionomercementincorporatedwithcationicsubstances
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Physical and mechanical properties of conventional glass ionomer cement incorporated with cationic substances

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