Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical diagnosis to show that tissue volume changes ap...

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Autores principales:	Taylor W. Schmitz, R. Nathan Spreng, The Alzheimer's Disease Neuroimaging Initiative
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f93fe3d502994e0f8e3ee52d71cd8dcf
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spelling	oai:doaj.org-article:f93fe3d502994e0f8e3ee52d71cd8dcf2021-12-02T14:38:35ZBasal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology10.1038/ncomms132492041-1723https://doaj.org/article/f93fe3d502994e0f8e3ee52d71cd8dcf2016-11-01T00:00:00Zhttps://doi.org/10.1038/ncomms13249https://doaj.org/toc/2041-1723Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical diagnosis to show that tissue volume changes appear earlier in the basal forebrain than in the entorhinal cortex.Taylor W. SchmitzR. Nathan SprengThe Alzheimer's Disease Neuroimaging InitiativeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Taylor W. Schmitz R. Nathan Spreng The Alzheimer's Disease Neuroimaging Initiative Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
description	Whether Alzheimer’s disease originates in basal forebrain or entorhinal cortex remains highly debated. Here the authors use structural magnetic resonance data from a longitudinal sample of participants stratified by cerebrospinal biomarker and clinical diagnosis to show that tissue volume changes appear earlier in the basal forebrain than in the entorhinal cortex.
format	article
author	Taylor W. Schmitz R. Nathan Spreng The Alzheimer's Disease Neuroimaging Initiative
author_facet	Taylor W. Schmitz R. Nathan Spreng The Alzheimer's Disease Neuroimaging Initiative
author_sort	Taylor W. Schmitz
title	Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
title_short	Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
title_full	Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
title_fullStr	Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
title_full_unstemmed	Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology
title_sort	basal forebrain degeneration precedes and predicts the cortical spread of alzheimer’s pathology
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f93fe3d502994e0f8e3ee52d71cd8dcf
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Basal forebrain degeneration precedes and predicts the cortical spread of Alzheimer’s pathology

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