A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon

A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon

The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which is conserved across bacteria.

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Autores principales: Yonatan Chemla, Michael Peeri, Mathias Luidor Heltberg, Jerry Eichler, Mogens Høgh Jensen, Tamir Tuller, Lital Alfonta
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/f945cec54ed844a3bf6360085372dfe1
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spelling oai:doaj.org-article:f945cec54ed844a3bf6360085372dfe12021-12-02T15:15:05ZA possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon10.1038/s41467-020-18577-42041-1723https://doaj.org/article/f945cec54ed844a3bf6360085372dfe12020-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-18577-4https://doaj.org/toc/2041-1723The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which is conserved across bacteria.Yonatan ChemlaMichael PeeriMathias Luidor HeltbergJerry EichlerMogens Høgh JensenTamir TullerLital AlfontaNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yonatan Chemla
Michael Peeri
Mathias Luidor Heltberg
Jerry Eichler
Mogens Høgh Jensen
Tamir Tuller
Lital Alfonta
A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
description The mechanisms for regulating translation re-initiation in bacteria remain poorly understood. Here, the authors screened a library of synthetic operons and identified a ribosome termination structure that modulates re-initiation efficiency and which is conserved across bacteria.
format article
author Yonatan Chemla
Michael Peeri
Mathias Luidor Heltberg
Jerry Eichler
Mogens Høgh Jensen
Tamir Tuller
Lital Alfonta
author_facet Yonatan Chemla
Michael Peeri
Mathias Luidor Heltberg
Jerry Eichler
Mogens Høgh Jensen
Tamir Tuller
Lital Alfonta
author_sort Yonatan Chemla
title A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
title_short A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
title_full A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
title_fullStr A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
title_full_unstemmed A possible universal role for mRNA secondary structure in bacterial translation revealed using a synthetic operon
title_sort possible universal role for mrna secondary structure in bacterial translation revealed using a synthetic operon
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/f945cec54ed844a3bf6360085372dfe1
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