Candida albicans gains azole resistance by altering sphingolipid composition

Candida albicans gains azole resistance by altering sphingolipid composition

The fungal pathogen Candida albicans is diploid, which hinders genome-wide studies. Here, Gao et al. present a piggyBac transposon-mediated mutagenesis system using stable haploid C. albicans strains, and use it to identify genes and mechanisms underlying azole resistance.

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Detalles Bibliográficos
Autores principales: Jiaxin Gao, Haitao Wang, Zeyao Li, Ada Hang-Heng Wong, Yi-Zheng Wang, Yahui Guo, Xin Lin, Guisheng Zeng, Haoping Liu, Yue Wang, Jianbin Wang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2018
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/f9482aff0bce438592c86a1e3d00feb0
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