Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

Cellular fusion is fundamental for skeletal muscle development. Here the authors show that myomerger is expressed in myoblasts, is essential for myoblast fusion in mice, and in co-operation with myomaker confers fusogenic ability to non-fusogenic cells.

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Autores principales:	Malgorzata E. Quinn, Qingnian Goh, Mitsutoshi Kurosaka, Dilani G. Gamage, Michael J. Petrany, Vikram Prasad, Douglas P. Millay
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9517f4aa0cf41ccb0945886204443b1
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spelling	oai:doaj.org-article:f9517f4aa0cf41ccb0945886204443b12021-12-02T17:06:06ZMyomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development10.1038/ncomms156652041-1723https://doaj.org/article/f9517f4aa0cf41ccb0945886204443b12017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15665https://doaj.org/toc/2041-1723Cellular fusion is fundamental for skeletal muscle development. Here the authors show that myomerger is expressed in myoblasts, is essential for myoblast fusion in mice, and in co-operation with myomaker confers fusogenic ability to non-fusogenic cells.Malgorzata E. QuinnQingnian GohMitsutoshi KurosakaDilani G. GamageMichael J. PetranyVikram PrasadDouglas P. MillayNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Malgorzata E. Quinn Qingnian Goh Mitsutoshi Kurosaka Dilani G. Gamage Michael J. Petrany Vikram Prasad Douglas P. Millay Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
description	Cellular fusion is fundamental for skeletal muscle development. Here the authors show that myomerger is expressed in myoblasts, is essential for myoblast fusion in mice, and in co-operation with myomaker confers fusogenic ability to non-fusogenic cells.
format	article
author	Malgorzata E. Quinn Qingnian Goh Mitsutoshi Kurosaka Dilani G. Gamage Michael J. Petrany Vikram Prasad Douglas P. Millay
author_facet	Malgorzata E. Quinn Qingnian Goh Mitsutoshi Kurosaka Dilani G. Gamage Michael J. Petrany Vikram Prasad Douglas P. Millay
author_sort	Malgorzata E. Quinn
title	Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
title_short	Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
title_full	Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
title_fullStr	Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
title_full_unstemmed	Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
title_sort	myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f9517f4aa0cf41ccb0945886204443b1
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Myomerger induces fusion of non-fusogenic cells and is required for skeletal muscle development

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