The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data.

The epidermal growth factor receptor (EGFR) signaling pathway is probably the best-studied receptor system in mammalian cells, and it also has become a popular example for employing mathematical modeling to cellular signaling networks. Dynamic models have the highest explanatory and predictive poten...

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Auteurs principaux: Regina Samaga, Julio Saez-Rodriguez, Leonidas G Alexopoulos, Peter K Sorger, Steffen Klamt
Format: article
Langue:EN
Publié: Public Library of Science (PLoS) 2009
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Accès en ligne:https://doaj.org/article/f9531926b64a4f3a912a451d245c5df1
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