Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses

The COVID-19 pandemic has deeply influenced sanitization procedures, and high-level disinfection has been massively used to prevent SARS-CoV-2 spread, with potential negative impact on the environment and on the threat of antimicrobial resistance (AMR). Aiming to overcome these concerns, yet preserv...

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Autores principales:	Maria D’Accolti, Irene Soffritti, Francesco Bonfante, Walter Ricciardi, Sante Mazzacane, Elisabetta Caselli
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	enveloped virus decontamination SARS-CoV-2 inactivation prevention infection control eco-friendly disinfection Microbiology QR1-502
Acceso en línea:	https://doaj.org/article/f954fcd9ec844eefae8c396e2400beb6
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spelling	oai:doaj.org-article:f954fcd9ec844eefae8c396e2400beb62021-11-25T19:13:30ZPotential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses10.3390/v131122271999-4915https://doaj.org/article/f954fcd9ec844eefae8c396e2400beb62021-11-01T00:00:00Zhttps://www.mdpi.com/1999-4915/13/11/2227https://doaj.org/toc/1999-4915The COVID-19 pandemic has deeply influenced sanitization procedures, and high-level disinfection has been massively used to prevent SARS-CoV-2 spread, with potential negative impact on the environment and on the threat of antimicrobial resistance (AMR). Aiming to overcome these concerns, yet preserving the effectiveness of sanitization against enveloped viruses, we assessed the antiviral properties of the Probiotic Cleaning Hygiene System (PCHS), an eco-sustainable probiotic-based detergent previously proven to stably abate pathogen contamination and AMR. PCHS (diluted 1:10, 1:50 and 1:100) was tested in comparison to common disinfectants (70% ethanol and 0.5% sodium hypochlorite), in suspension and carrier tests, according with the European UNI EN 14476:2019 and UNI EN 16777:2019 standards. Human alpha- and beta-coronaviruses hCoV-229E and SARS-CoV-2, human herpesvirus type 1, human and animal influenza viruses, and vaccinia virus were included in the study. The results showed that PCHS was able to inactivate 99.99% of all tested viruses within 1–2 h of contact, both in suspension and on surface. Notably, while control disinfectants became inactive within 2 h after application, the PCHS antiviral action persisted up to 24 h post-application, suggesting that its use may effectively allow a continuous prevention of virus spread via contaminated environment, without worsening environmental pollution and AMR concern.Maria D’AccoltiIrene SoffrittiFrancesco BonfanteWalter RicciardiSante MazzacaneElisabetta CaselliMDPI AGarticleenveloped virus decontaminationSARS-CoV-2 inactivationpreventioninfection controleco-friendly disinfectionMicrobiologyQR1-502ENViruses, Vol 13, Iss 2227, p 2227 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	enveloped virus decontamination SARS-CoV-2 inactivation prevention infection control eco-friendly disinfection Microbiology QR1-502
spellingShingle	enveloped virus decontamination SARS-CoV-2 inactivation prevention infection control eco-friendly disinfection Microbiology QR1-502 Maria D’Accolti Irene Soffritti Francesco Bonfante Walter Ricciardi Sante Mazzacane Elisabetta Caselli Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
description	The COVID-19 pandemic has deeply influenced sanitization procedures, and high-level disinfection has been massively used to prevent SARS-CoV-2 spread, with potential negative impact on the environment and on the threat of antimicrobial resistance (AMR). Aiming to overcome these concerns, yet preserving the effectiveness of sanitization against enveloped viruses, we assessed the antiviral properties of the Probiotic Cleaning Hygiene System (PCHS), an eco-sustainable probiotic-based detergent previously proven to stably abate pathogen contamination and AMR. PCHS (diluted 1:10, 1:50 and 1:100) was tested in comparison to common disinfectants (70% ethanol and 0.5% sodium hypochlorite), in suspension and carrier tests, according with the European UNI EN 14476:2019 and UNI EN 16777:2019 standards. Human alpha- and beta-coronaviruses hCoV-229E and SARS-CoV-2, human herpesvirus type 1, human and animal influenza viruses, and vaccinia virus were included in the study. The results showed that PCHS was able to inactivate 99.99% of all tested viruses within 1–2 h of contact, both in suspension and on surface. Notably, while control disinfectants became inactive within 2 h after application, the PCHS antiviral action persisted up to 24 h post-application, suggesting that its use may effectively allow a continuous prevention of virus spread via contaminated environment, without worsening environmental pollution and AMR concern.
format	article
author	Maria D’Accolti Irene Soffritti Francesco Bonfante Walter Ricciardi Sante Mazzacane Elisabetta Caselli
author_facet	Maria D’Accolti Irene Soffritti Francesco Bonfante Walter Ricciardi Sante Mazzacane Elisabetta Caselli
author_sort	Maria D’Accolti
title	Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
title_short	Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
title_full	Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
title_fullStr	Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
title_full_unstemmed	Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses
title_sort	potential of an eco-sustainable probiotic-cleaning formulation in reducing infectivity of enveloped viruses
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/f954fcd9ec844eefae8c396e2400beb6
work_keys_str_mv	AT mariadaccolti potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses AT irenesoffritti potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses AT francescobonfante potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses AT walterricciardi potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses AT santemazzacane potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses AT elisabettacaselli potentialofanecosustainableprobioticcleaningformulationinreducinginfectivityofenvelopedviruses
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Potential of an Eco-Sustainable Probiotic-Cleaning Formulation in Reducing Infectivity of Enveloped Viruses

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