Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry

Personalized medicine requires accurate and ethnicity-optimized reference genome panels. Here, the Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA) evaluates typical variant filters and existing genome databases against newly sequenced African-ancestry populations.

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Auteurs principaux: Michael D. Kessler, Laura Yerges-Armstrong, Margaret A. Taub, Amol C. Shetty, Kristin Maloney, Linda Jo Bone Jeng, Ingo Ruczinski, Albert M. Levin, L. Keoki Williams, Terri H. Beaty, Rasika A. Mathias, Kathleen C. Barnes, Consortium on Asthma among African-ancestry Populations in the Americas (CAAPA), Timothy D. O’Connor
Format: article
Langue:EN
Publié: Nature Portfolio 2016
Sujets:
Science
Q
Accès en ligne:https://doaj.org/article/f9576b534da64e5a9b33c002e1f226f9
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