ACTIVATION OF GENES CONTROLLING THE IMMUNE SIGNALING PATHWAYS: DIFFERENTIAL INDIVIDUAL SENSITIVITY OF HUMAN BLOOD CELLS FOR INTERFERON PREPARATIONS AND IFN INDUCERS

We have studied dose effects of several Interferon (IFN) inducers, i.e., Genfaxon (beta-1 IFN), Cycloferon and Immunomax upon expression of six genes controlling the signaling in immune pathways (TLR3, TLR4, RIG1, IRF3, IPS, B2M), by means of real-time RT-PCR, being tested with blood cells from thre...

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Autores principales: T. M. Sokolova, A. N. Shuvalov, I. M. Shapoval, Z. A. Sokolova, F. I. Ershov
Formato: article
Lenguaje:RU
Publicado: SPb RAACI 2015
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Acceso en línea:https://doaj.org/article/f95f6d44700d42359a77ba8391da8e2d
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