The Rhoptry Pseudokinase ROP54 Modulates <named-content content-type="genus-species">Toxoplasma gondii</named-content> Virulence and Host GBP2 Loading

The Rhoptry Pseudokinase ROP54 Modulates <named-content content-type="genus-species">Toxoplasma gondii</named-content> Virulence and Host GBP2 Loading

ABSTRACT Toxoplasma gondii uses unique secretory organelles called rhoptries to inject an array of effector proteins into the host cytoplasm that hijack host cell functions. We have discovered a novel rhoptry pseudokinase effector, ROP54, which is injected into the host cell upon invasion and traffi...

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Autores principales: Elliot W. Kim, Santhosh M. Nadipuram, Ashley L. Tetlow, William D. Barshop, Philip T. Liu, James A. Wohlschlegel, Peter J. Bradley
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2016
Materias:
Toxoplasma gondii
guanylate binding proteins
immunity-related GTPases
pseudokinase
rhoptry
virulence
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/f969dd0a7b064a0e898dc43410fb7afe
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