Activation of SGK1.1 Upregulates the M-current in the Presence of Epilepsy Mutations
In the central nervous system, the M-current plays a critical role in regulating subthreshold electrical excitability of neurons, determining their firing properties and responsiveness to synaptic input. The M-channel is mainly formed by subunits Kv7.2 and Kv7.3 that co-assemble to form a heterotetr...
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| Main Authors: | , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
Frontiers Media S.A.
2021
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| Subjects: | |
| Online Access: | https://doaj.org/article/f97174501a0741d39ac4467b2b44bfa8 |
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