Systemic blockade of P2X7 receptor protects against sepsis-induced intestinal barrier disruption
Abstract Sepsis, during which the intestinal epithelial barrier is frequently disrupted, remains a challenging and life-threatening problem in clinical practice. The P2X7 receptor (P2X7R) is a non-selective adenosine triphosphate-gated cation channel present in macrophages that is involved in inflam...
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Autores principales: | , , , , , , , , , |
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Formato: | article |
Lenguaje: | EN |
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Nature Portfolio
2017
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Materias: | |
Acceso en línea: | https://doaj.org/article/f977ba3be8c943cc8d7dc7deee0d72ec |
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