Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution

Abstract The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal gl...

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Autores principales:	Konstantin N. Semenov, Daria A. Ivanova, Sergei V. Ageev, Andrey V. Petrov, Nikita E. Podolsky, Ekaterina M. Volochaeva, Ekaterina M. Fedorova, Anatolii A. Meshcheriakov, Egor E. Zakharov, Igor V. Murin, Vladimir V. Sharoyko
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f97ab02f5a164988922bba43382e3f73
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spelling	oai:doaj.org-article:f97ab02f5a164988922bba43382e3f732021-12-02T15:51:15ZEvaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution10.1038/s41598-021-87014-32045-2322https://doaj.org/article/f97ab02f5a164988922bba43382e3f732021-04-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-87014-3https://doaj.org/toc/2045-2322Abstract The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.Konstantin N. SemenovDaria A. IvanovaSergei V. AgeevAndrey V. PetrovNikita E. PodolskyEkaterina M. VolochaevaEkaterina M. FedorovaAnatolii A. MeshcheriakovEgor E. ZakharovIgor V. MurinVladimir V. SharoykoNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Konstantin N. Semenov Daria A. Ivanova Sergei V. Ageev Andrey V. Petrov Nikita E. Podolsky Ekaterina M. Volochaeva Ekaterina M. Fedorova Anatolii A. Meshcheriakov Egor E. Zakharov Igor V. Murin Vladimir V. Sharoyko Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
description	Abstract The article is devoted to the study of the pharmacokinetics of fullerene C60 in oil and micellar forms, analysis of its content in blood, liver, lungs, kidneys, heart, brain, adrenal glands, thymus, testicles, and spleen. The highest accumulation of C60 was found in the liver and adrenal glands. As a result of the studies carried out, it was shown that the bioavailability of C60 in the micellar form is higher than that in an oil solution.
format	article
author	Konstantin N. Semenov Daria A. Ivanova Sergei V. Ageev Andrey V. Petrov Nikita E. Podolsky Ekaterina M. Volochaeva Ekaterina M. Fedorova Anatolii A. Meshcheriakov Egor E. Zakharov Igor V. Murin Vladimir V. Sharoyko
author_facet	Konstantin N. Semenov Daria A. Ivanova Sergei V. Ageev Andrey V. Petrov Nikita E. Podolsky Ekaterina M. Volochaeva Ekaterina M. Fedorova Anatolii A. Meshcheriakov Egor E. Zakharov Igor V. Murin Vladimir V. Sharoyko
author_sort	Konstantin N. Semenov
title	Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
title_short	Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
title_full	Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
title_fullStr	Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
title_full_unstemmed	Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution
title_sort	evaluation of the c60 biodistribution in mice in a micellar extraox form and in an oil solution
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f97ab02f5a164988922bba43382e3f73
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Evaluation of the C60 biodistribution in mice in a micellar ExtraOx form and in an oil solution

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