Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis

Inflammasomes are involved in gut homeostasis and inflammatory pathologies. The authors show that a hyperactive NLRP3 inflammasome maintains gut homeostasis through remodelling of the gut microbiota and induction of regulatory T cells.

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Detalles Bibliográficos
Autores principales:	Xiaomin Yao, Chenhong Zhang, Yue Xing, Guang Xue, Qianpeng Zhang, Fengwei Pan, Guojun Wu, Yingxin Hu, Qiuhong Guo, Ailing Lu, Xiaoming Zhang, Rongbin Zhou, Zhigang Tian, Benhua Zeng, Hong Wei, Warren Strober, Liping Zhao, Guangxun Meng
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f97bce19ba0642ea8e7aaf262df4cb10
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spelling	oai:doaj.org-article:f97bce19ba0642ea8e7aaf262df4cb102021-12-02T14:41:07ZRemodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis10.1038/s41467-017-01917-22041-1723https://doaj.org/article/f97bce19ba0642ea8e7aaf262df4cb102017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01917-2https://doaj.org/toc/2041-1723Inflammasomes are involved in gut homeostasis and inflammatory pathologies. The authors show that a hyperactive NLRP3 inflammasome maintains gut homeostasis through remodelling of the gut microbiota and induction of regulatory T cells.Xiaomin YaoChenhong ZhangYue XingGuang XueQianpeng ZhangFengwei PanGuojun WuYingxin HuQiuhong GuoAiling LuXiaoming ZhangRongbin ZhouZhigang TianBenhua ZengHong WeiWarren StroberLiping ZhaoGuangxun MengNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Xiaomin Yao Chenhong Zhang Yue Xing Guang Xue Qianpeng Zhang Fengwei Pan Guojun Wu Yingxin Hu Qiuhong Guo Ailing Lu Xiaoming Zhang Rongbin Zhou Zhigang Tian Benhua Zeng Hong Wei Warren Strober Liping Zhao Guangxun Meng Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
description	Inflammasomes are involved in gut homeostasis and inflammatory pathologies. The authors show that a hyperactive NLRP3 inflammasome maintains gut homeostasis through remodelling of the gut microbiota and induction of regulatory T cells.
format	article
author	Xiaomin Yao Chenhong Zhang Yue Xing Guang Xue Qianpeng Zhang Fengwei Pan Guojun Wu Yingxin Hu Qiuhong Guo Ailing Lu Xiaoming Zhang Rongbin Zhou Zhigang Tian Benhua Zeng Hong Wei Warren Strober Liping Zhao Guangxun Meng
author_facet	Xiaomin Yao Chenhong Zhang Yue Xing Guang Xue Qianpeng Zhang Fengwei Pan Guojun Wu Yingxin Hu Qiuhong Guo Ailing Lu Xiaoming Zhang Rongbin Zhou Zhigang Tian Benhua Zeng Hong Wei Warren Strober Liping Zhao Guangxun Meng
author_sort	Xiaomin Yao
title	Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
title_short	Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
title_full	Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
title_fullStr	Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
title_full_unstemmed	Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis
title_sort	remodelling of the gut microbiota by hyperactive nlrp3 induces regulatory t cells to maintain homeostasis
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f97bce19ba0642ea8e7aaf262df4cb10
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Remodelling of the gut microbiota by hyperactive NLRP3 induces regulatory T cells to maintain homeostasis

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