GlmS and NagB regulate amino sugar metabolism in opposing directions and affect Streptococcus mutans virulence.
Streptococcus mutans is a cariogenic pathogen that produces an extracellular polysaccharide (glucan) from dietary sugars, which allows it to establish a reproductive niche and secrete acids that degrade tooth enamel. While two enzymes (GlmS and NagB) are known to be key factors affecting the entranc...
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Main Authors: | Miki Kawada-Matsuo, Yusuke Mazda, Yuichi Oogai, Mikihito Kajiya, Toshihisa Kawai, Sakuo Yamada, Shouichi Miyawaki, Takahiko Oho, Hitoshi Komatsuzawa |
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Format: | article |
Language: | EN |
Published: |
Public Library of Science (PLoS)
2012
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Online Access: | https://doaj.org/article/f97d30a20ff24a79ab5bef37172eabf6 |
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