Cooperative binding.

Molecular binding is an interaction between molecules that results in a stable association between those molecules. Cooperative binding occurs if the number of binding sites of a macromolecule that are occupied by a specific type of ligand is a nonlinear function of this ligand's concentration....

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Autores principales:	Melanie I Stefan, Nicolas Le Novère
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2013
Materias:	Biology (General) QH301-705.5
Acceso en línea:	https://doaj.org/article/f97e7b74fd5e4da9a2a7ad0682baa302
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spelling	oai:doaj.org-article:f97e7b74fd5e4da9a2a7ad0682baa3022021-11-18T05:52:03ZCooperative binding.1553-734X1553-735810.1371/journal.pcbi.1003106https://doaj.org/article/f97e7b74fd5e4da9a2a7ad0682baa3022013-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23843752/?tool=EBIhttps://doaj.org/toc/1553-734Xhttps://doaj.org/toc/1553-7358Molecular binding is an interaction between molecules that results in a stable association between those molecules. Cooperative binding occurs if the number of binding sites of a macromolecule that are occupied by a specific type of ligand is a nonlinear function of this ligand's concentration. This can be due, for instance, to an affinity for the ligand that depends on the amount of ligand bound. Cooperativity can be positive (supralinear) or negative (infralinear). Cooperative binding is most often observed in proteins, but nucleic acids can also exhibit cooperative binding, for instance of transcription factors. Cooperative binding has been shown to be the mechanism underlying a large range of biochemical and physiological processes.Melanie I StefanNicolas Le NovèrePublic Library of Science (PLoS)articleBiology (General)QH301-705.5ENPLoS Computational Biology, Vol 9, Iss 6, p e1003106 (2013)
institution	DOAJ
collection	DOAJ
language	EN
topic	Biology (General) QH301-705.5
spellingShingle	Biology (General) QH301-705.5 Melanie I Stefan Nicolas Le Novère Cooperative binding.
description	Molecular binding is an interaction between molecules that results in a stable association between those molecules. Cooperative binding occurs if the number of binding sites of a macromolecule that are occupied by a specific type of ligand is a nonlinear function of this ligand's concentration. This can be due, for instance, to an affinity for the ligand that depends on the amount of ligand bound. Cooperativity can be positive (supralinear) or negative (infralinear). Cooperative binding is most often observed in proteins, but nucleic acids can also exhibit cooperative binding, for instance of transcription factors. Cooperative binding has been shown to be the mechanism underlying a large range of biochemical and physiological processes.
format	article
author	Melanie I Stefan Nicolas Le Novère
author_facet	Melanie I Stefan Nicolas Le Novère
author_sort	Melanie I Stefan
title	Cooperative binding.
title_short	Cooperative binding.
title_full	Cooperative binding.
title_fullStr	Cooperative binding.
title_full_unstemmed	Cooperative binding.
title_sort	cooperative binding.
publisher	Public Library of Science (PLoS)
publishDate	2013
url	https://doaj.org/article/f97e7b74fd5e4da9a2a7ad0682baa302
work_keys_str_mv	AT melanieistefan cooperativebinding AT nicolaslenovere cooperativebinding
_version_	1718424766057021440

Cooperative binding.

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