Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Late-onset Alzheimer's disease (LOAD) is a complex multi-factorial disorder. Here, the authors perform a data-driven analysis of LOAD progression, including multimodal brain imaging, plasma and CSF biomarkers, and find vascular dysfunction is among the earliest and strongest altered events.

Guardado en:

Detalles Bibliográficos
Autores principales:	Y. Iturria-Medina, R. C. Sotero, P. J. Toussaint, J. M. Mateos-Pérez, A. C. Evans, The Alzheimer’s Disease Neuroimaging Initiative
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f989313352764f0e97879fa2389c24b5
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:f989313352764f0e97879fa2389c24b5
record_format	dspace
spelling	oai:doaj.org-article:f989313352764f0e97879fa2389c24b52021-12-02T17:32:35ZEarly role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis10.1038/ncomms119342041-1723https://doaj.org/article/f989313352764f0e97879fa2389c24b52016-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms11934https://doaj.org/toc/2041-1723Late-onset Alzheimer's disease (LOAD) is a complex multi-factorial disorder. Here, the authors perform a data-driven analysis of LOAD progression, including multimodal brain imaging, plasma and CSF biomarkers, and find vascular dysfunction is among the earliest and strongest altered events.Y. Iturria-MedinaR. C. SoteroP. J. ToussaintJ. M. Mateos-PérezA. C. EvansThe Alzheimer’s Disease Neuroimaging InitiativeNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Y. Iturria-Medina R. C. Sotero P. J. Toussaint J. M. Mateos-Pérez A. C. Evans The Alzheimer’s Disease Neuroimaging Initiative Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
description	Late-onset Alzheimer's disease (LOAD) is a complex multi-factorial disorder. Here, the authors perform a data-driven analysis of LOAD progression, including multimodal brain imaging, plasma and CSF biomarkers, and find vascular dysfunction is among the earliest and strongest altered events.
format	article
author	Y. Iturria-Medina R. C. Sotero P. J. Toussaint J. M. Mateos-Pérez A. C. Evans The Alzheimer’s Disease Neuroimaging Initiative
author_facet	Y. Iturria-Medina R. C. Sotero P. J. Toussaint J. M. Mateos-Pérez A. C. Evans The Alzheimer’s Disease Neuroimaging Initiative
author_sort	Y. Iturria-Medina
title	Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
title_short	Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
title_full	Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
title_fullStr	Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
title_full_unstemmed	Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis
title_sort	early role of vascular dysregulation on late-onset alzheimer’s disease based on multifactorial data-driven analysis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/f989313352764f0e97879fa2389c24b5
work_keys_str_mv	AT yiturriamedina earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis AT rcsotero earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis AT pjtoussaint earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis AT jmmateosperez earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis AT acevans earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis AT thealzheimersdiseaseneuroimaginginitiative earlyroleofvasculardysregulationonlateonsetalzheimersdiseasebasedonmultifactorialdatadrivenanalysis
_version_	1718380284021309440

Early role of vascular dysregulation on late-onset Alzheimer’s disease based on multifactorial data-driven analysis

Ejemplares similares