Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary...
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| Autores principales: | , , , , , |
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| Formato: | article |
| Lenguaje: | EN |
| Publicado: |
Nature Portfolio
2020
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| Materias: | |
| Acceso en línea: | https://doaj.org/article/f9896b6049de47a5a5a06fb0398c126b |
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| Sumario: | It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary changes in signaling modes. |
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