Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development

It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary...

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Autores principales:	Gregory A. Cary, Brenna S. McCauley, Olga Zueva, Joseph Pattinato, William Longabaugh, Veronica F. Hinman
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2020
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9896b6049de47a5a5a06fb0398c126b
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spelling	oai:doaj.org-article:f9896b6049de47a5a5a06fb0398c126b2021-12-02T15:39:26ZSystematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development10.1038/s41467-020-20023-42041-1723https://doaj.org/article/f9896b6049de47a5a5a06fb0398c126b2020-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20023-4https://doaj.org/toc/2041-1723It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary changes in signaling modes.Gregory A. CaryBrenna S. McCauleyOlga ZuevaJoseph PattinatoWilliam LongabaughVeronica F. HinmanNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Gregory A. Cary Brenna S. McCauley Olga Zueva Joseph Pattinato William Longabaugh Veronica F. Hinman Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
description	It is unclear how a gene regulatory network (GRN) incorporates novelty whilst still maintaining overall stability. Here, the authors provide a comprehensive GRN for endomesoderm specification in the sea star from zygote stage to gastrulation, showing conserved network kernels stabilize evolutionary changes in signaling modes.
format	article
author	Gregory A. Cary Brenna S. McCauley Olga Zueva Joseph Pattinato William Longabaugh Veronica F. Hinman
author_facet	Gregory A. Cary Brenna S. McCauley Olga Zueva Joseph Pattinato William Longabaugh Veronica F. Hinman
author_sort	Gregory A. Cary
title	Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
title_short	Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
title_full	Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
title_fullStr	Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
title_full_unstemmed	Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
title_sort	systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development
publisher	Nature Portfolio
publishDate	2020
url	https://doaj.org/article/f9896b6049de47a5a5a06fb0398c126b
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Systematic comparison of sea urchin and sea star developmental gene regulatory networks explains how novelty is incorporated in early development

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