Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data

Abstract The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8–10 mm), Grade C (5–8 mm), and Grade D (< 5 mm, normal). To ide...

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Autores principales:	Lili He, Yinghua Sun, Guoying Huang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/f990673e2add497196aaf5e4362caa21
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spelling	oai:doaj.org-article:f990673e2add497196aaf5e4362caa212021-12-02T10:49:34ZIdentifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data10.1038/s41598-021-81339-92045-2322https://doaj.org/article/f990673e2add497196aaf5e4362caa212021-01-01T00:00:00Zhttps://doi.org/10.1038/s41598-021-81339-9https://doaj.org/toc/2045-2322Abstract The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8–10 mm), Grade C (5–8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-ALNs, the prevalence of each grade was compared between asymptomatic individuals and symptomatic (e.g., abdominal pain) individuals without other diseases (e.g., appendicitis) that could explain the symptoms for different ages using data from > 200,000 individuals. The results showed the following: (1) For ages 1–3 years, the recommended threshold size is 8 mm, as the differences in the prevalence between the two groups were nonsignificant for Grade C but significant (p < 0.05) for both Grades A and B. (2) For ages 3–14 years, the recommended threshold size is 5 mm, as the differences between the two groups were significant (p < 0.05) for Grades A, B, and C. (3) The prevalence of Grades A, B, and C was very low for ages 0–1 years and high for ages 1–6 years. (4) The prevalence for males was generally higher than that for females for Grades A and B.Lili HeYinghua SunGuoying HuangNature PortfolioarticleMedicineRScienceQENScientific Reports, Vol 11, Iss 1, Pp 1-7 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Lili He Yinghua Sun Guoying Huang Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
description	Abstract The threshold size for enlarged abdominal lymph nodes (E-ALNs), a common pediatric disorder, has yet to be standardized. According to the maximum short-axis diameter, this study divided ALNs into Grade A (≥ 10 mm), Grade B (8–10 mm), Grade C (5–8 mm), and Grade D (< 5 mm, normal). To identify the threshold size for E-ALNs, the prevalence of each grade was compared between asymptomatic individuals and symptomatic (e.g., abdominal pain) individuals without other diseases (e.g., appendicitis) that could explain the symptoms for different ages using data from > 200,000 individuals. The results showed the following: (1) For ages 1–3 years, the recommended threshold size is 8 mm, as the differences in the prevalence between the two groups were nonsignificant for Grade C but significant (p < 0.05) for both Grades A and B. (2) For ages 3–14 years, the recommended threshold size is 5 mm, as the differences between the two groups were significant (p < 0.05) for Grades A, B, and C. (3) The prevalence of Grades A, B, and C was very low for ages 0–1 years and high for ages 1–6 years. (4) The prevalence for males was generally higher than that for females for Grades A and B.
format	article
author	Lili He Yinghua Sun Guoying Huang
author_facet	Lili He Yinghua Sun Guoying Huang
author_sort	Lili He
title	Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
title_short	Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
title_full	Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
title_fullStr	Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
title_full_unstemmed	Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
title_sort	identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/f990673e2add497196aaf5e4362caa21
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Identifying threshold sizes for enlarged abdominal lymph nodes in different age ranges from about 200,000 individual’s data

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