Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals

The genomic organization and origin of the avenacin biosynthetic gene cluster remain unknown. Here, the authors assemble the genome of diploid oat Avena strigosa, reveal the structure and organization of the consecutive genes, characterize the last two missing pathway steps, and investigate the orig...

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Autores principales: Yan Li, Aymeric Leveau, Qiang Zhao, Qi Feng, Hengyun Lu, Jiashun Miao, Zheyong Xue, Azahara C. Martin, Eva Wegel, Jing Wang, Anastasia Orme, Maria-Dolores Rey, Miroslava Karafiátová, Jan Vrána, Burkhard Steuernagel, Ryan Joynson, Charlotte Owen, James Reed, Thomas Louveau, Michael J. Stephenson, Lei Zhang, Xuehui Huang, Tao Huang, Danling Fan, Congcong Zhou, Qilin Tian, Wenjun Li, Yiqi Lu, Jiaying Chen, Yan Zhao, Ying Lu, Chuanrang Zhu, Zhenhua Liu, Guy Polturak, Rebecca Casson, Lionel Hill, Graham Moore, Rachel Melton, Neil Hall, Brande B. H. Wulff, Jaroslav Doležel, Tim Langdon, Bin Han, Anne Osbourn
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Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f99572e4267d4d05946048bdc463db23
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spelling oai:doaj.org-article:f99572e4267d4d05946048bdc463db232021-12-02T16:49:06ZSubtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals10.1038/s41467-021-22920-82041-1723https://doaj.org/article/f99572e4267d4d05946048bdc463db232021-05-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22920-8https://doaj.org/toc/2041-1723The genomic organization and origin of the avenacin biosynthetic gene cluster remain unknown. Here, the authors assemble the genome of diploid oat Avena strigosa, reveal the structure and organization of the consecutive genes, characterize the last two missing pathway steps, and investigate the origin of the pathway in cereals.Yan LiAymeric LeveauQiang ZhaoQi FengHengyun LuJiashun MiaoZheyong XueAzahara C. MartinEva WegelJing WangAnastasia OrmeMaria-Dolores ReyMiroslava KarafiátováJan VránaBurkhard SteuernagelRyan JoynsonCharlotte OwenJames ReedThomas LouveauMichael J. StephensonLei ZhangXuehui HuangTao HuangDanling FanCongcong ZhouQilin TianWenjun LiYiqi LuJiaying ChenYan ZhaoYing LuChuanrang ZhuZhenhua LiuGuy PolturakRebecca CassonLionel HillGraham MooreRachel MeltonNeil HallBrande B. H. WulffJaroslav DoleželTim LangdonBin HanAnne OsbournNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Yan Li
Aymeric Leveau
Qiang Zhao
Qi Feng
Hengyun Lu
Jiashun Miao
Zheyong Xue
Azahara C. Martin
Eva Wegel
Jing Wang
Anastasia Orme
Maria-Dolores Rey
Miroslava Karafiátová
Jan Vrána
Burkhard Steuernagel
Ryan Joynson
Charlotte Owen
James Reed
Thomas Louveau
Michael J. Stephenson
Lei Zhang
Xuehui Huang
Tao Huang
Danling Fan
Congcong Zhou
Qilin Tian
Wenjun Li
Yiqi Lu
Jiaying Chen
Yan Zhao
Ying Lu
Chuanrang Zhu
Zhenhua Liu
Guy Polturak
Rebecca Casson
Lionel Hill
Graham Moore
Rachel Melton
Neil Hall
Brande B. H. Wulff
Jaroslav Doležel
Tim Langdon
Bin Han
Anne Osbourn
Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
description The genomic organization and origin of the avenacin biosynthetic gene cluster remain unknown. Here, the authors assemble the genome of diploid oat Avena strigosa, reveal the structure and organization of the consecutive genes, characterize the last two missing pathway steps, and investigate the origin of the pathway in cereals.
format article
author Yan Li
Aymeric Leveau
Qiang Zhao
Qi Feng
Hengyun Lu
Jiashun Miao
Zheyong Xue
Azahara C. Martin
Eva Wegel
Jing Wang
Anastasia Orme
Maria-Dolores Rey
Miroslava Karafiátová
Jan Vrána
Burkhard Steuernagel
Ryan Joynson
Charlotte Owen
James Reed
Thomas Louveau
Michael J. Stephenson
Lei Zhang
Xuehui Huang
Tao Huang
Danling Fan
Congcong Zhou
Qilin Tian
Wenjun Li
Yiqi Lu
Jiaying Chen
Yan Zhao
Ying Lu
Chuanrang Zhu
Zhenhua Liu
Guy Polturak
Rebecca Casson
Lionel Hill
Graham Moore
Rachel Melton
Neil Hall
Brande B. H. Wulff
Jaroslav Doležel
Tim Langdon
Bin Han
Anne Osbourn
author_facet Yan Li
Aymeric Leveau
Qiang Zhao
Qi Feng
Hengyun Lu
Jiashun Miao
Zheyong Xue
Azahara C. Martin
Eva Wegel
Jing Wang
Anastasia Orme
Maria-Dolores Rey
Miroslava Karafiátová
Jan Vrána
Burkhard Steuernagel
Ryan Joynson
Charlotte Owen
James Reed
Thomas Louveau
Michael J. Stephenson
Lei Zhang
Xuehui Huang
Tao Huang
Danling Fan
Congcong Zhou
Qilin Tian
Wenjun Li
Yiqi Lu
Jiaying Chen
Yan Zhao
Ying Lu
Chuanrang Zhu
Zhenhua Liu
Guy Polturak
Rebecca Casson
Lionel Hill
Graham Moore
Rachel Melton
Neil Hall
Brande B. H. Wulff
Jaroslav Doležel
Tim Langdon
Bin Han
Anne Osbourn
author_sort Yan Li
title Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
title_short Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
title_full Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
title_fullStr Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
title_full_unstemmed Subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
title_sort subtelomeric assembly of a multi-gene pathway for antimicrobial defense compounds in cereals
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f99572e4267d4d05946048bdc463db23
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