Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals
Identifying causal variants and genes in genome-wide association studies remains a challenge, an issue that is ameliorated with larger sample sizes. Here the authors meta-analyze kidney function genome-wide association studies to identify new loci and fine-map loci to home in on variants and genes i...
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Nature Portfolio
2021
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oai:doaj.org-article:f9a7445b1e5c4729b2f89352fcb65ca12021-12-02T17:01:21ZDiscovery and prioritization of variants and genes for kidney function in >1.2 million individuals10.1038/s41467-021-24491-02041-1723https://doaj.org/article/f9a7445b1e5c4729b2f89352fcb65ca12021-07-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-24491-0https://doaj.org/toc/2041-1723Identifying causal variants and genes in genome-wide association studies remains a challenge, an issue that is ameliorated with larger sample sizes. Here the authors meta-analyze kidney function genome-wide association studies to identify new loci and fine-map loci to home in on variants and genes involved in kidney function.Kira J. StanzickYong LiPascal SchlosserMathias GorskiMatthias WuttkeLaurent F. ThomasHumaira RasheedBryce X. RowanSarah E. GrahamBrett R. VanderweffSnehal B. PatilVA Million Veteran ProgramCassiane Robinson-CohenJohn M. GazianoChristopher J. O’DonnellCristen J. WillerStein HallanBjørn Olav ÅsvoldAndre GessnerAdriana M. HungCristian PattaroAnna KöttgenKlaus J. StarkIris M. HeidThomas W. WinklerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021) |
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DOAJ |
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EN |
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Science Q |
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Science Q Kira J. Stanzick Yong Li Pascal Schlosser Mathias Gorski Matthias Wuttke Laurent F. Thomas Humaira Rasheed Bryce X. Rowan Sarah E. Graham Brett R. Vanderweff Snehal B. Patil VA Million Veteran Program Cassiane Robinson-Cohen John M. Gaziano Christopher J. O’Donnell Cristen J. Willer Stein Hallan Bjørn Olav Åsvold Andre Gessner Adriana M. Hung Cristian Pattaro Anna Köttgen Klaus J. Stark Iris M. Heid Thomas W. Winkler Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| description |
Identifying causal variants and genes in genome-wide association studies remains a challenge, an issue that is ameliorated with larger sample sizes. Here the authors meta-analyze kidney function genome-wide association studies to identify new loci and fine-map loci to home in on variants and genes involved in kidney function. |
| format |
article |
| author |
Kira J. Stanzick Yong Li Pascal Schlosser Mathias Gorski Matthias Wuttke Laurent F. Thomas Humaira Rasheed Bryce X. Rowan Sarah E. Graham Brett R. Vanderweff Snehal B. Patil VA Million Veteran Program Cassiane Robinson-Cohen John M. Gaziano Christopher J. O’Donnell Cristen J. Willer Stein Hallan Bjørn Olav Åsvold Andre Gessner Adriana M. Hung Cristian Pattaro Anna Köttgen Klaus J. Stark Iris M. Heid Thomas W. Winkler |
| author_facet |
Kira J. Stanzick Yong Li Pascal Schlosser Mathias Gorski Matthias Wuttke Laurent F. Thomas Humaira Rasheed Bryce X. Rowan Sarah E. Graham Brett R. Vanderweff Snehal B. Patil VA Million Veteran Program Cassiane Robinson-Cohen John M. Gaziano Christopher J. O’Donnell Cristen J. Willer Stein Hallan Bjørn Olav Åsvold Andre Gessner Adriana M. Hung Cristian Pattaro Anna Köttgen Klaus J. Stark Iris M. Heid Thomas W. Winkler |
| author_sort |
Kira J. Stanzick |
| title |
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| title_short |
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| title_full |
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| title_fullStr |
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| title_full_unstemmed |
Discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| title_sort |
discovery and prioritization of variants and genes for kidney function in >1.2 million individuals |
| publisher |
Nature Portfolio |
| publishDate |
2021 |
| url |
https://doaj.org/article/f9a7445b1e5c4729b2f89352fcb65ca1 |
| work_keys_str_mv |
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