Protein-directed ribosomal frameshifting temporally regulates gene expression

Programmed −1 ribosomal frameshifting (−1 PRF) is a mechanism whereby specific signals within mRNAs direct ribosomes to shift into an alternative reading frame. Here the authors describe a mechanism of −1 PRF that is temporally regulated by a viral protein over the course of the virus replicative cy...

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Autores principales:	Sawsan Napthine, Roger Ling, Leanne K. Finch, Joshua D. Jones, Susanne Bell, Ian Brierley, Andrew E. Firth
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/f9a75c9002d24e00ad9f8ed2e273754a
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spelling	oai:doaj.org-article:f9a75c9002d24e00ad9f8ed2e273754a2021-12-02T17:06:18ZProtein-directed ribosomal frameshifting temporally regulates gene expression10.1038/ncomms155822041-1723https://doaj.org/article/f9a75c9002d24e00ad9f8ed2e273754a2017-06-01T00:00:00Zhttps://doi.org/10.1038/ncomms15582https://doaj.org/toc/2041-1723Programmed −1 ribosomal frameshifting (−1 PRF) is a mechanism whereby specific signals within mRNAs direct ribosomes to shift into an alternative reading frame. Here the authors describe a mechanism of −1 PRF that is temporally regulated by a viral protein over the course of the virus replicative cycle.Sawsan NapthineRoger LingLeanne K. FinchJoshua D. JonesSusanne BellIan BrierleyAndrew E. FirthNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Sawsan Napthine Roger Ling Leanne K. Finch Joshua D. Jones Susanne Bell Ian Brierley Andrew E. Firth Protein-directed ribosomal frameshifting temporally regulates gene expression
description	Programmed −1 ribosomal frameshifting (−1 PRF) is a mechanism whereby specific signals within mRNAs direct ribosomes to shift into an alternative reading frame. Here the authors describe a mechanism of −1 PRF that is temporally regulated by a viral protein over the course of the virus replicative cycle.
format	article
author	Sawsan Napthine Roger Ling Leanne K. Finch Joshua D. Jones Susanne Bell Ian Brierley Andrew E. Firth
author_facet	Sawsan Napthine Roger Ling Leanne K. Finch Joshua D. Jones Susanne Bell Ian Brierley Andrew E. Firth
author_sort	Sawsan Napthine
title	Protein-directed ribosomal frameshifting temporally regulates gene expression
title_short	Protein-directed ribosomal frameshifting temporally regulates gene expression
title_full	Protein-directed ribosomal frameshifting temporally regulates gene expression
title_fullStr	Protein-directed ribosomal frameshifting temporally regulates gene expression
title_full_unstemmed	Protein-directed ribosomal frameshifting temporally regulates gene expression
title_sort	protein-directed ribosomal frameshifting temporally regulates gene expression
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/f9a75c9002d24e00ad9f8ed2e273754a
work_keys_str_mv	AT sawsannapthine proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT rogerling proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT leannekfinch proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT joshuadjones proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT susannebell proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT ianbrierley proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression AT andrewefirth proteindirectedribosomalframeshiftingtemporallyregulatesgeneexpression
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Protein-directed ribosomal frameshifting temporally regulates gene expression

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