Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS

Recent double-blind, randomized, controlled trials reported that human umbilical cord-derived mesenchymal stem cell (MSC) infusions in COVID-19 patients with acute respiratory distress syndrome (ARDS) could diminish cytokine storm and lung damage. While these outcomes are significant, additional pha...

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Autores principales: Ashok K. Shetty, Padmashri A. Shetty, Gabriele Zanirati, Kunlin Jin
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/f9ac2c2e383640f791789acba4296424
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spelling oai:doaj.org-article:f9ac2c2e383640f791789acba42964242021-12-02T17:19:43ZFurther validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS10.1038/s41536-021-00161-z2057-3995https://doaj.org/article/f9ac2c2e383640f791789acba42964242021-09-01T00:00:00Zhttps://doi.org/10.1038/s41536-021-00161-zhttps://doaj.org/toc/2057-3995Recent double-blind, randomized, controlled trials reported that human umbilical cord-derived mesenchymal stem cell (MSC) infusions in COVID-19 patients with acute respiratory distress syndrome (ARDS) could diminish cytokine storm and lung damage. While these outcomes are significant, additional phase II/III trials are required to validate the efficacy of MSCs to improve the survival of COVID-19 patients with ARDS. Future studies also need to assess the efficacy of MSCs to prevent long COVID.Ashok K. ShettyPadmashri A. ShettyGabriele ZaniratiKunlin JinNature PortfolioarticleMedicineRENnpj Regenerative Medicine, Vol 6, Iss 1, Pp 1-3 (2021)
institution DOAJ
collection DOAJ
language EN
topic Medicine
R
spellingShingle Medicine
R
Ashok K. Shetty
Padmashri A. Shetty
Gabriele Zanirati
Kunlin Jin
Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
description Recent double-blind, randomized, controlled trials reported that human umbilical cord-derived mesenchymal stem cell (MSC) infusions in COVID-19 patients with acute respiratory distress syndrome (ARDS) could diminish cytokine storm and lung damage. While these outcomes are significant, additional phase II/III trials are required to validate the efficacy of MSCs to improve the survival of COVID-19 patients with ARDS. Future studies also need to assess the efficacy of MSCs to prevent long COVID.
format article
author Ashok K. Shetty
Padmashri A. Shetty
Gabriele Zanirati
Kunlin Jin
author_facet Ashok K. Shetty
Padmashri A. Shetty
Gabriele Zanirati
Kunlin Jin
author_sort Ashok K. Shetty
title Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
title_short Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
title_full Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
title_fullStr Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
title_full_unstemmed Further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in COVID-19 patients with ARDS
title_sort further validation of the efficacy of mesenchymal stem cell infusions for reducing mortality in covid-19 patients with ards
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/f9ac2c2e383640f791789acba4296424
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AT gabrielezanirati furthervalidationoftheefficacyofmesenchymalstemcellinfusionsforreducingmortalityincovid19patientswithards
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