Critical role of backbone coordination in the mRNA recognition by RNA induced silencing complex

Critical role of backbone coordination in the mRNA recognition by RNA induced silencing complex

Lizhe Zhu et al. use a quasi Markov State Model built from extensive molecular dynamics simulations to elucidate the dynamics of RISC-mRNA interactions. Their results provide further insight on how a target nucleotide is positioned before recognition by Argonaute.

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Detalles Bibliográficos
Autores principales: Lizhe Zhu, Hanlun Jiang, Siqin Cao, Ilona Christy Unarta, Xin Gao, Xuhui Huang
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Biology (General)
QH301-705.5
Acceso en línea:https://doaj.org/article/f9b08be56b81469197c788250c9a00d7
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