Successful Milk Oral Immunotherapy Promotes Generation of Casein-Specific CD137+ FOXP3+ Regulatory T Cells Detectable in Peripheral Blood
BackgroundOral immunotherapy (OIT) is an emerging treatment for cow’s milk protein (CMP) allergy in children. The mechanisms driving tolerance following OIT are not well understood. Regulatory T cells (TREG) cells are key inhibitors of allergic responses and promoters of allergen-specific tolerance....
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Main Authors: | Yi Zhang, Lei Li, Geneviève Genest, Wei Zhao, Dan Ke, Sabrina Bartolucci, Nils Pavey, Tho-Alfakar Al-Aubodah, Duncan Lejtenyi, Bahar Torabi, Moshe Ben-Shoshan, Bruce Mazer, Ciriaco A. Piccirillo |
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Format: | article |
Language: | EN |
Published: |
Frontiers Media S.A.
2021
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Online Access: | https://doaj.org/article/f9b863f16fe24acabcc832c2ecdfd742 |
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